{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Chen HM"],"funding":["Yunnan Department of Science and Technology | Applied Basic Research Foundation of Yunnan Province (Yunnan Province Applied and Basic Research Foundation)","Yunnan Provincial Science and Technology Department (Yunnan Department of Science and Technology)","Natural Science Foundation of Yunnan Province (Yunnan Provincial Natural Science Foundation)"],"pagination":["1345"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11655879"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["11(1)"],"pubmed_abstract":["The Banna miniature inbred pig (BN) is an intensively inbred line for biomedical research and xenotransplantation due to its low individual variation and stable genetic background. Although it is originated from the Diannan miniature pig (DN), substantial genetic changes have actually occurred. However, the lack of a BN reference genome has limited studies on the complete genomic architecture and utilization as a biomedical model. Here, we present a high-quality genome for BN using PacBio HiFi and Hi-C sequencing technologies, with a total length of 2.66 Gb, a scaffold N50 of 143.60 Mb, and 97.59% of the sequences anchored to chromosomes. Its BUSCO score is 96.30%, higher than porcine reference assembly and DN. The genome contains 48.49% of repeats, 19,756 protein-coding genes, and 7,207 n"],"journal":["Scientific data"],"pubmed_title":["A chromosome-scale reference genome of the Banna miniature inbred pig."],"pmcid":["PMC11655879"],"funding_grant_id":["202102AA100054","202301AW070012","202305AH340006","202102AA310047"],"pubmed_authors":["Wang MS","Zhao HY","Liu ZX","Chen HM","Peng GY","Si S","Jamal MA","Wei HJ","Wang P","Lv MJ","Jiao DL","Yan C","Zeng YZ","Xu KX","Zhao H"],"additional_accession":[]},"is_claimable":false,"name":"A chromosome-scale reference genome of the Banna miniature inbred pig.","description":"The Banna miniature inbred pig (BN) is an intensively inbred line for biomedical research and xenotransplantation due to its low individual variation and stable genetic background. Although it is originated from the Diannan miniature pig (DN), substantial genetic changes have actually occurred. However, the lack of a BN reference genome has limited studies on the complete genomic architecture and utilization as a biomedical model. Here, we present a high-quality genome for BN using PacBio HiFi and Hi-C sequencing technologies, with a total length of 2.66 Gb, a scaffold N50 of 143.60 Mb, and 97.59% of the sequences anchored to chromosomes. Its BUSCO score is 96.30%, higher than porcine reference assembly and DN. The genome contains 48.49% of repeats, 19,756 protein-coding genes, and 7,207 n","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Dec","modification":"2026-04-08T19:45:41.555Z","creation":"2025-04-07T00:32:30.421Z"},"accession":"S-EPMC11655879","cross_references":{"pubmed":["39695204"],"doi":["10.1038/s41597-024-04201-3"]}}