biostudies-literatureXia YYunnan Province Science and Technology DepartmentMajor science and technology special plan project of Yunnan ProvinceNational Key Project of Research and Development Plan during the fourteenth Five-year Plan Period3461https://www.ebi.ac.uk/biostudies/studies/S-EPMC11657382biostudies-literatureUnknown24(1)<h4>Background</h4>Available evidence falls short in assessing the risk of long-term outcomes among individuals with hypertension residing at various altitudes. We aimed to investigate the association between residential altitude and the risk of all-cause and cardiovascular disease (CVD) mortality among hypertensive patients.<h4>Methods</h4>This cohort study encompassed 67,275 hypertensive patients aged ≥35 years who participated in China's Basic Public Health Service Program in 2018. Participants were categorized into four groups based on their residence altitude: <500 m, 500-1,499 m, 1,500-2,500 m, and > 2,500 m. The associations between residential altitude and the risks of all-cause and CVD mortality were analyzed using Cox proportional hazards regression models. The dose-response relaBMC public healthAssociation of altitude with all-cause and cardiovascular mortality among patients with hypertension: a cohort study in Southwest China.PMC116573822022YFC2503400202103AF140002202302AA310045202103AC100004Xia YPan XTang MLuo ZMa MPang LWang HHe LZhu DDuo LfalseAssociation of altitude with all-cause and cardiovascular mortality among patients with hypertension: a cohort study in Southwest China.<h4>Background</h4>Available evidence falls short in assessing the risk of long-term outcomes among individuals with hypertension residing at various altitudes. We aimed to investigate the association between residential altitude and the risk of all-cause and cardiovascular disease (CVD) mortality among hypertensive patients.<h4>Methods</h4>This cohort study encompassed 67,275 hypertensive patients aged ≥35 years who participated in China's Basic Public Health Service Program in 2018. Participants were categorized into four groups based on their residence altitude: <500 m, 500-1,499 m, 1,500-2,500 m, and > 2,500 m. The associations between residential altitude and the risks of all-cause and CVD mortality were analyzed using Cox proportional hazards regression models. The dose-response rela2024-01-01T00:00:00Z2024 Dec2025-04-26T17:01:24.153Z2025-04-06T15:25:13.755ZS-EPMC116573823969606910.1186/s12889-024-20891-1