biostudies-literatureSorce LRNational Heart, Lung, and Blood Institute and the National Institute of Nursing Research, National Institutes of HealthNHLBI NIH HHSDiane Cronin-Stubbs Memorial Award, Rush University College of NursingDean's Scholarship, Rush University College of Nursing (Sorce)Medela Nursing Research Scholars Grant (Sorce)e13103https://www.ebi.ac.uk/biostudies/studies/S-EPMC11669727biostudies-literatureUnknown30(2)<h4>Background</h4>Data support the protective effects of human breast milk (HBM) feeding in acute illness but little is known about the impact of HBM feeding on the criticality of infants.<h4>Aim</h4>To explore the relationship between early HBM feeding and severity of illness and recovery in critically ill children requiring intubation and mechanical ventilation for acute respiratory failure (ARF).<h4>Study design</h4>Prospective cohort study of mothers of patients aged 1-36 months who participated in the acute and follow-up phases of the Randomized Evaluation of Sedation Titration for Respiratory Failure (RESTORE) clinical trial. Participants completed a survey describing HBM dose fed during their infant's first month of life.<h4>Results</h4>Of 138 patients, 70 (51%) received exclusive Nursing in critical careInfant feeding and criticality in children.PMC11669727U01 HL086649HL086649U01 HL086622Sorce LRAsaro LACurley MAQRESTORE Study InvestigatorsfalseInfant feeding and criticality in children.<h4>Background</h4>Data support the protective effects of human breast milk (HBM) feeding in acute illness but little is known about the impact of HBM feeding on the criticality of infants.<h4>Aim</h4>To explore the relationship between early HBM feeding and severity of illness and recovery in critically ill children requiring intubation and mechanical ventilation for acute respiratory failure (ARF).<h4>Study design</h4>Prospective cohort study of mothers of patients aged 1-36 months who participated in the acute and follow-up phases of the Randomized Evaluation of Sedation Titration for Respiratory Failure (RESTORE) clinical trial. Participants completed a survey describing HBM dose fed during their infant's first month of life.<h4>Results</h4>Of 138 patients, 70 (51%) received exclusive 2025-01-01T00:00:00Z2025 Mar2026-07-16T23:05:33.259Z2025-04-04T02:45:31.669ZS-EPMC116697273892309910.1111/nicc.13103