biostudies-literatureUnknown19(12)Khaled MDeGroote Institute of Pain Research and CareMeditech International IncorporatedHamilton Academic Health Sciences OrganizationSouthern Ontario Pharmaceutical and Health Innovation Ecosystem<h4>Background</h4>Caesarean section (CS) is the most common inpatient surgical procedure performed in Canada. CS is known to cause moderate-to-severe pain, which is suggested to be associated with postpartum depression and persistent pain. Existing limitations in multimodal analgesia and conscious attempts to avoid opioids highlight the need for non-pharmacological strategies. Photobiomodulation therapy (PBMT) uses light-emitting diode (LED) and laser and has suggested potential for improving pain control and wound healing. This study aims to evaluate the effectiveness of PBMT as part of existing multimodal analgesia after elective CSs.<h4>Methods</h4>This placebo-controlled, two-arm, multi-centre, parallel-design randomized controlled trial includes women aged ≥16 years with planned CS uPloS onee0314010https://www.ebi.ac.uk/biostudies/studies/S-EPMC11670968biostudies-literaturePhotobiomodulation as part of multimodal analgesia to improve pain relief and wound healing after elective caesarean section: A protocol for randomized controlled trial.PMC11670968Diaz ACordovani DSharma SEwusie JEChan JShanthanna HFarsinejad PBaranov AKazi AHunjan SKhatana KSelvanayagam SKhaled MGnanapragasam ALuketic LMuhsen ZPatel MClements SfalsePhotobiomodulation as part of multimodal analgesia to improve pain relief and wound healing after elective caesarean section: A protocol for randomized controlled trial.<h4>Background</h4>Caesarean section (CS) is the most common inpatient surgical procedure performed in Canada. CS is known to cause moderate-to-severe pain, which is suggested to be associated with postpartum depression and persistent pain. Existing limitations in multimodal analgesia and conscious attempts to avoid opioids highlight the need for non-pharmacological strategies. Photobiomodulation therapy (PBMT) uses light-emitting diode (LED) and laser and has suggested potential for improving pain control and wound healing. This study aims to evaluate the effectiveness of PBMT as part of existing multimodal analgesia after elective CSs.<h4>Methods</h4>This placebo-controlled, two-arm, multi-centre, parallel-design randomized controlled trial includes women aged ≥16 years with planned CS u2024-01-01T00:00:00Z20242026-06-01T18:09:07.348Z2025-04-19T21:31:17.147ZS-EPMC116709683972402010.1371/journal.pone.0314010