{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zeng D"],"funding":["Science and Technology Planning Project of Guangdong Province","National Natural Science Foundation of China","China Postdoctoral Science Foundation"],"pagination":["146-151"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11672007"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["109(1)"],"pubmed_abstract":["<h4>Aim</h4>To investigate the association of floor area ratio (FAR), an indicator of built environments, and myopia onset.<h4>Methods</h4>This prospective cohort study recruited 136 753 children aged 6-10 years from 108 schools in Shenzhen, China at baseline (2016-2017). Refractive power was measured with non-cycloplegic autorefraction over a 2-year follow-up period. FAR was objectively evaluated using geographical information system technology. Mixed-effects logistic regression models were constructed to examine the association of FAR with a 2-year cumulative incidence of myopia among individuals without baseline myopia; multiple linear regression model, with a 2-year cumulative incidence rate of myopia at each school.<h4>Results</h4>Of 101 624 non-myopic children (56.3% boys; mean (SE) age, 7.657±1.182 years) included in the study, 26 391 (26.0%) of them developed myopia after 2 years. In the individual-level analysis adjusting for demographic, socioeconomic and greenness factors, an IQR in FAR was associated with a decreased risk of 2-year myopia incidence (OR 0.898, 95% CI 0.866 to 0.932, p<0.001). Similar findings were observed in the analysis additionally adjusted for genetic and behavioural factors (OR 0.821, 95% CI 0.766 to 0.880, p<0.001). In the school-level, an IQR increase in FAR was found to be associated with a 2.0% reduction in the 2-year incidence rate of myopia (95% CI 1.3% to 2.6%, p<0.001).<h4>Conclusions</h4>Exposure to higher FAR was associated with a decreased myopia incidence, providing insights into myopia prevention through school built environments in China."],"journal":["The British journal of ophthalmology"],"pubmed_title":["Shaping school for childhood myopia: the association between floor area ratio of school environment and myopia in China."],"pmcid":["PMC11672007"],"funding_grant_id":["82371111","2023B1515020100","2023M734047","82301266","82171035","2021B1212010003","2023A1111120011","82301265","92368205"],"pubmed_authors":["Yun D","Yang Y","Zhao L","Lin D","Liao H","Xu A","Zhang X","Chen W","Shang Y","Lin H","Wang X","Zeng D","Tang Y"],"additional_accession":[]},"is_claimable":false,"name":"Shaping school for childhood myopia: the association between floor area ratio of school environment and myopia in China.","description":"<h4>Aim</h4>To investigate the association of floor area ratio (FAR), an indicator of built environments, and myopia onset.<h4>Methods</h4>This prospective cohort study recruited 136 753 children aged 6-10 years from 108 schools in Shenzhen, China at baseline (2016-2017). Refractive power was measured with non-cycloplegic autorefraction over a 2-year follow-up period. FAR was objectively evaluated using geographical information system technology. Mixed-effects logistic regression models were constructed to examine the association of FAR with a 2-year cumulative incidence of myopia among individuals without baseline myopia; multiple linear regression model, with a 2-year cumulative incidence rate of myopia at each school.<h4>Results</h4>Of 101 624 non-myopic children (56.3% boys; mean (SE) age, 7.657±1.182 years) included in the study, 26 391 (26.0%) of them developed myopia after 2 years. In the individual-level analysis adjusting for demographic, socioeconomic and greenness factors, an IQR in FAR was associated with a decreased risk of 2-year myopia incidence (OR 0.898, 95% CI 0.866 to 0.932, p<0.001). Similar findings were observed in the analysis additionally adjusted for genetic and behavioural factors (OR 0.821, 95% CI 0.766 to 0.880, p<0.001). In the school-level, an IQR increase in FAR was found to be associated with a 2.0% reduction in the 2-year incidence rate of myopia (95% CI 1.3% to 2.6%, p<0.001).<h4>Conclusions</h4>Exposure to higher FAR was associated with a decreased myopia incidence, providing insights into myopia prevention through school built environments in China.","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Dec","modification":"2025-04-04T02:14:27.19Z","creation":"2025-04-04T02:14:27.19Z"},"accession":"S-EPMC11672007","cross_references":{"pubmed":["38955480"],"doi":["10.1136/bjo-2024-325448"]}}