biostudies-literatureZeng DScience and Technology Planning Project of Guangdong ProvinceNational Natural Science Foundation of ChinaChina Postdoctoral Science Foundation146-151https://www.ebi.ac.uk/biostudies/studies/S-EPMC11672007biostudies-literatureUnknown109(1)<h4>Aim</h4>To investigate the association of floor area ratio (FAR), an indicator of built environments, and myopia onset.<h4>Methods</h4>This prospective cohort study recruited 136 753 children aged 6-10 years from 108 schools in Shenzhen, China at baseline (2016-2017). Refractive power was measured with non-cycloplegic autorefraction over a 2-year follow-up period. FAR was objectively evaluated using geographical information system technology. Mixed-effects logistic regression models were constructed to examine the association of FAR with a 2-year cumulative incidence of myopia among individuals without baseline myopia; multiple linear regression model, with a 2-year cumulative incidence rate of myopia at each school.<h4>Results</h4>Of 101 624 non-myopic children (56.3% boys; mean (SE) age, 7.657±1.182 years) included in the study, 26 391 (26.0%) of them developed myopia after 2 years. In the individual-level analysis adjusting for demographic, socioeconomic and greenness factors, an IQR in FAR was associated with a decreased risk of 2-year myopia incidence (OR 0.898, 95% CI 0.866 to 0.932, p<0.001). Similar findings were observed in the analysis additionally adjusted for genetic and behavioural factors (OR 0.821, 95% CI 0.766 to 0.880, p<0.001). In the school-level, an IQR increase in FAR was found to be associated with a 2.0% reduction in the 2-year incidence rate of myopia (95% CI 1.3% to 2.6%, p<0.001).<h4>Conclusions</h4>Exposure to higher FAR was associated with a decreased myopia incidence, providing insights into myopia prevention through school built environments in China.The British journal of ophthalmologyShaping school for childhood myopia: the association between floor area ratio of school environment and myopia in China.PMC11672007823711112023B15150201002023M73404782301266821710352021B12120100032023A11111200118230126592368205Yun DYang YZhao LLin DLiao HXu AZhang XChen WShang YLin HWang XZeng DTang YfalseShaping school for childhood myopia: the association between floor area ratio of school environment and myopia in China.<h4>Aim</h4>To investigate the association of floor area ratio (FAR), an indicator of built environments, and myopia onset.<h4>Methods</h4>This prospective cohort study recruited 136 753 children aged 6-10 years from 108 schools in Shenzhen, China at baseline (2016-2017). Refractive power was measured with non-cycloplegic autorefraction over a 2-year follow-up period. FAR was objectively evaluated using geographical information system technology. Mixed-effects logistic regression models were constructed to examine the association of FAR with a 2-year cumulative incidence of myopia among individuals without baseline myopia; multiple linear regression model, with a 2-year cumulative incidence rate of myopia at each school.<h4>Results</h4>Of 101 624 non-myopic children (56.3% boys; mean (SE) age, 7.657±1.182 years) included in the study, 26 391 (26.0%) of them developed myopia after 2 years. In the individual-level analysis adjusting for demographic, socioeconomic and greenness factors, an IQR in FAR was associated with a decreased risk of 2-year myopia incidence (OR 0.898, 95% CI 0.866 to 0.932, p<0.001). Similar findings were observed in the analysis additionally adjusted for genetic and behavioural factors (OR 0.821, 95% CI 0.766 to 0.880, p<0.001). In the school-level, an IQR increase in FAR was found to be associated with a 2.0% reduction in the 2-year incidence rate of myopia (95% CI 1.3% to 2.6%, p<0.001).<h4>Conclusions</h4>Exposure to higher FAR was associated with a decreased myopia incidence, providing insights into myopia prevention through school built environments in China.2024-01-01T00:00:00Z2024 Dec2025-04-04T02:14:27.19Z2025-04-04T02:14:27.19ZS-EPMC116720073895548010.1136/bjo-2024-325448