{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhang X"],"funding":["Project of the Science and Technology Program of Shaanxi Academy of Science","Xi'an Innovation Capacity Foundation Strengthening Plan-Agricultural Technology Research and Development Project","Natural Science Basic Research Program of Shaanxi"],"pagination":["1599"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11676476"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(12)"],"pubmed_abstract":["<i>Gynostemma pentaphyllum</i> is a traditional Chinese medicinal plant of considerable application value and commercial potential, primarily due to its production of various bioactive compounds, particularly dammarane-type triterpenoid saponins that are structurally analogous to ginsenosides. Oxidosqualene cyclase (OSC), a pivotal enzyme in the biosynthesis of triterpenoid metabolites in plants, catalyzes the conversion of oxidosqualene into triterpenoid precursors, which are essential components of the secondary metabolites found in <i>G. pentaphyllum</i>. To elucidate the role of <i>OSC</i> gene family members in the synthesis of gypenosides within <i>G. pentaphyllum</i>, this study undertook a comprehensive genome-wide identification and characterization of <i>OSC</i> genes within <i>G"],"journal":["Life (Basel, Switzerland)"],"pubmed_title":["Genome-Wide Identification and Characterization of <i>OSC</i> Gene Family in <i>Gynostemma pentaphyllum</i> (Cucurbitaceae)."],"pmcid":["PMC11676476"],"funding_grant_id":["2023-JC-QN-0220","2021JH-05-0062","2024k-32"],"pubmed_authors":["Yang H","Zhang X","Wang X","Chen C"],"additional_accession":[]},"is_claimable":false,"name":"Genome-Wide Identification and Characterization of <i>OSC</i> Gene Family in <i>Gynostemma pentaphyllum</i> (Cucurbitaceae).","description":"<i>Gynostemma pentaphyllum</i> is a traditional Chinese medicinal plant of considerable application value and commercial potential, primarily due to its production of various bioactive compounds, particularly dammarane-type triterpenoid saponins that are structurally analogous to ginsenosides. Oxidosqualene cyclase (OSC), a pivotal enzyme in the biosynthesis of triterpenoid metabolites in plants, catalyzes the conversion of oxidosqualene into triterpenoid precursors, which are essential components of the secondary metabolites found in <i>G. pentaphyllum</i>. To elucidate the role of <i>OSC</i> gene family members in the synthesis of gypenosides within <i>G. pentaphyllum</i>, this study undertook a comprehensive genome-wide identification and characterization of <i>OSC</i> genes within <i>G","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Dec","modification":"2026-05-23T03:20:17.509Z","creation":"2026-05-23T03:08:19.366Z"},"accession":"S-EPMC11676476","cross_references":{"pubmed":["39768308"],"doi":["10.3390/life14121599"]}}