biostudies-literatureJiang SInnovative Research Programme of Xiangyang No.1 People's HospitalHubei Provincial Natural Science Foundation30660https://www.ebi.ac.uk/biostudies/studies/S-EPMC11680988biostudies-literatureUnknown14(1)The current study was to explore the prevalence and risk factors elements of pre-frailty and frailty among patients undergoing hemodialysis (HD) in central China. A cross-sectional, multi-institutional investigation was conducted. From March to May 2024, using the convenience sampling method, a total of 408 HD patients from four hospitals in Xiangyang, China, were recruited for this study. The participants' demographics, lifestyle factors, factors related to dialysis treatment, the FRAIL scale, psychological resilience, and medical coping modes were assessed using a questionnaire. Multi-categorical logistic regression was performed to examine factors associated with pre-frailty and frailty in this population. Furthermore, to evaluate the independent relationship between frailty and psycholScientific reportsPrevalence and risk factors of pre-frailty and frailty in hemodialysis patients in central China.PMC11680988XYY2023SD112022CFB873Jiang YQiu XXie YQiu QZhang NJiang SZhou YZhang SRao LfalsePrevalence and risk factors of pre-frailty and frailty in hemodialysis patients in central China.The current study was to explore the prevalence and risk factors elements of pre-frailty and frailty among patients undergoing hemodialysis (HD) in central China. A cross-sectional, multi-institutional investigation was conducted. From March to May 2024, using the convenience sampling method, a total of 408 HD patients from four hospitals in Xiangyang, China, were recruited for this study. The participants' demographics, lifestyle factors, factors related to dialysis treatment, the FRAIL scale, psychological resilience, and medical coping modes were assessed using a questionnaire. Multi-categorical logistic regression was performed to examine factors associated with pre-frailty and frailty in this population. Furthermore, to evaluate the independent relationship between frailty and psychol2024-01-01T00:00:00Z2024 Dec2025-04-27T01:37:42.817Z2025-04-06T18:18:32.367ZS-EPMC116809883973045810.1038/s41598-024-79855-5