{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["57(24)"],"submitter":["Shannon DP"],"pubmed_abstract":["Bioinspired hydroxypyridinone (HOPO)functionalized materials are shown to display a remarkable capacity for stability and for chelating a wide array of metal ions. This allows for the synthesis of multifunctional networks with diverse physical properties when compared to traditional catechol systems. In the present study, we report a facile, one-pot synthesis of an amino HOPO ligand and simple, scalable incorporation into PEG-acrylate based networks via active ester chemistry. This modular network approach allows for fabrication of patterned HOPO containing networks which can chelate a range of metal ions, such as transition metals (Fe<sup>3+</sup>) and lanthanides (Ho<sup>3+</sup>, Tb<sup>3+</sup>), leading to modulation of mechanical, magnetic, and fluorescent properties. Moreover, networks with tailored, heterogeneous properties can be prepared through localization of metal ion incorporation in 3-dimensions via masking techniques, creating distinctly soft, hard, magnetic, and fluorescent domains."],"journal":["Macromolecules"],"pagination":["11339-11349"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11684171"],"repository":["biostudies-literature"],"pubmed_title":["Bioinspired Metal-Ligand Networks with Enhanced Stability and Performance: Facile Preparation of Hydroxypyridinone (HOPO)-Functionalized Materials."],"pmcid":["PMC11684171"],"pubmed_authors":["Shannon DP","Helgeson ME","Cerdan K","Chen Y","Su J","Mecklenburg M","Hawker CJ","Kim M","Valentine MT"],"additional_accession":[]},"is_claimable":false,"name":"Bioinspired Metal-Ligand Networks with Enhanced Stability and Performance: Facile Preparation of Hydroxypyridinone (HOPO)-Functionalized Materials.","description":"Bioinspired hydroxypyridinone (HOPO)functionalized materials are shown to display a remarkable capacity for stability and for chelating a wide array of metal ions. This allows for the synthesis of multifunctional networks with diverse physical properties when compared to traditional catechol systems. In the present study, we report a facile, one-pot synthesis of an amino HOPO ligand and simple, scalable incorporation into PEG-acrylate based networks via active ester chemistry. This modular network approach allows for fabrication of patterned HOPO containing networks which can chelate a range of metal ions, such as transition metals (Fe<sup>3+</sup>) and lanthanides (Ho<sup>3+</sup>, Tb<sup>3+</sup>), leading to modulation of mechanical, magnetic, and fluorescent properties. Moreover, networks with tailored, heterogeneous properties can be prepared through localization of metal ion incorporation in 3-dimensions via masking techniques, creating distinctly soft, hard, magnetic, and fluorescent domains.","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Dec","modification":"2026-06-02T02:02:25.422Z","creation":"2026-04-13T03:12:45.115Z"},"accession":"S-EPMC11684171","cross_references":{"pubmed":["39741960"],"doi":["10.1021/acs.macromol.4c02250"]}}