biostudies-literatureRumfelt KEEunice Shriver National Institute for Child Health and Human DevelopmentNICHD NIH HHSNCATS NIH HHSNationalWomen&apos;s Reproductive Health ResearchThrasher Research FundCenter for Advancing Translational Sciences of the National Institutes of Healthofae723https://www.ebi.ac.uk/biostudies/studies/S-EPMC11697169biostudies-literatureUnknown12(1)<h4>Background</h4>Immunization against influenza and respiratory syncytial virus (RSV) protects pregnant individuals and their infants against infection via transplacental transport of immunoglobulin G (IgG). We sought to evaluate the quantity and efficiency of maternal influenza- and RSV-specific IgG transfer in pregnancies with preterm and full-term deliveries.<h4>Methods</h4>Delivery samples from 115 maternal-infant pairs (2018-2021) were analyzed for RSV prefusion F and IAV-H3 and IAV-H1 antibodies using electrochemiluminescence assays. We used Wilcoxon rank sum tests, <i>t</i> tests, Pearson correlation coefficients (PCCs), and linear regression to evaluate distributions of IgG results by maternal influenza vaccination status and preterm birth (<37 weeks).<h4>Results</h4>ApproximatelOpen forum infectious diseasesMaternal-Infant Respiratory Syncytial Virus and Influenza A Virus Antibody Transfer in Preterm and Full-term Infants.PMC116971692 K12HD001264-21K12 HD001264UL1 TR002319Rumfelt KEStolarczuk JELauring ASEnglund JAKachikis ABPike MLekander AMartin ETEckert LOfalseMaternal-Infant Respiratory Syncytial Virus and Influenza A Virus Antibody Transfer in Preterm and Full-term Infants.<h4>Background</h4>Immunization against influenza and respiratory syncytial virus (RSV) protects pregnant individuals and their infants against infection via transplacental transport of immunoglobulin G (IgG). We sought to evaluate the quantity and efficiency of maternal influenza- and RSV-specific IgG transfer in pregnancies with preterm and full-term deliveries.<h4>Methods</h4>Delivery samples from 115 maternal-infant pairs (2018-2021) were analyzed for RSV prefusion F and IAV-H3 and IAV-H1 antibodies using electrochemiluminescence assays. We used Wilcoxon rank sum tests, <i>t</i> tests, Pearson correlation coefficients (PCCs), and linear regression to evaluate distributions of IgG results by maternal influenza vaccination status and preterm birth (<37 weeks).<h4>Results</h4>Approximatel2025-01-01T00:00:00Z2025 Jan2025-04-18T12:47:55.916Z2025-04-03T23:27:00.901ZS-EPMC116971693975874610.1093/ofid/ofae723