{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Yao Q"],"funding":["Radiumhemmets Forskningsfonder","China Sponsorship Council","Cancerfonden"],"pagination":["e1004505"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11706452"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["21(12)"],"pubmed_abstract":["<h4>Background</h4>Evidence on invasive cervical cancer prevention among older women is limited, especially with the introduction of human papillomavirus (HPV)-based screening and longer interval. We conducted a long-term follow-up of the first phase of a randomized healthcare policy trial in cervical screening, targeting women aged 56 to 61 years old, to investigate the effectiveness of primary HPV-based screening in preventing invasive cervical cancer (ICC) and the safety of extending screening interval.<h4>Methods and findings</h4>The randomized healthcare policy trial of primary HPV-based cervical screening targeted women residing in Stockholm-Gotland region during 2012 to 2016, aged 30 to 64 years. The trial aimed to investigate the detection rate of cervical intraepithelial neoplasia"],"journal":["PLoS medicine"],"pubmed_title":["Evaluation of primary HPV-based cervical screening among older women: Long-term follow-up of a randomized healthcare policy trial in Sweden."],"pmcid":["PMC11706452"],"funding_grant_id":["234172","202206160010","21 1690 Pj"],"pubmed_authors":["Dillner J","Elfstrom KM","Yao Q","Wang J","Strander B","Sundstrom K"],"additional_accession":[]},"is_claimable":false,"name":"Evaluation of primary HPV-based cervical screening among older women: Long-term follow-up of a randomized healthcare policy trial in Sweden.","description":"<h4>Background</h4>Evidence on invasive cervical cancer prevention among older women is limited, especially with the introduction of human papillomavirus (HPV)-based screening and longer interval. We conducted a long-term follow-up of the first phase of a randomized healthcare policy trial in cervical screening, targeting women aged 56 to 61 years old, to investigate the effectiveness of primary HPV-based screening in preventing invasive cervical cancer (ICC) and the safety of extending screening interval.<h4>Methods and findings</h4>The randomized healthcare policy trial of primary HPV-based cervical screening targeted women residing in Stockholm-Gotland region during 2012 to 2016, aged 30 to 64 years. The trial aimed to investigate the detection rate of cervical intraepithelial neoplasia","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Dec","modification":"2026-06-01T15:01:22.141Z","creation":"2025-04-04T21:49:18.708Z"},"accession":"S-EPMC11706452","cross_references":{"pubmed":["39700313"],"doi":["10.1371/journal.pmed.1004505"]}}