biostudies-literatureUnknown5(1)Segawa T<h4>Aims</h4>This study aimed to investigate the relationship between corticosteroid therapy and long-term outcomes in patients with cardiac sarcoidosis, stratified by left ventricular ejection fraction (LVEF) at diagnosis.<h4>Methods and results</h4>This study conducted a <i>post hoc</i> analysis of the ILLUstration of the Management and prognosIs of JapaNese PATiEnts with Cardiac Sarcoidosis, a retrospective multicentre registry. Cardiac sarcoidosis was diagnosed based on the 2016 Japanese Circulation Society and 2014 Heart Rhythm Society criteria. The primary endpoint was a composite of all-cause death, hospitalization for heart failure, and fatal ventricular arrhythmia events. Patients were divided into three groups based on LVEF: preserved LVEF (≥50%, <i>n</i> = 251), moderately impaiEuropean heart journal openoeae100https://www.ebi.ac.uk/biostudies/studies/S-EPMC11720171biostudies-literatureCorticosteroid therapy and long-term outcomes in patients with cardiac sarcoidosis stratified by left ventricular ejection fraction.PMC11720171Segawa TKitai TTanaka HBaba YNaruse YMatsue YSakata YTaniguchi TYoshioka KNabeta TOkumura TfalseCorticosteroid therapy and long-term outcomes in patients with cardiac sarcoidosis stratified by left ventricular ejection fraction.<h4>Aims</h4>This study aimed to investigate the relationship between corticosteroid therapy and long-term outcomes in patients with cardiac sarcoidosis, stratified by left ventricular ejection fraction (LVEF) at diagnosis.<h4>Methods and results</h4>This study conducted a <i>post hoc</i> analysis of the ILLUstration of the Management and prognosIs of JapaNese PATiEnts with Cardiac Sarcoidosis, a retrospective multicentre registry. Cardiac sarcoidosis was diagnosed based on the 2016 Japanese Circulation Society and 2014 Heart Rhythm Society criteria. The primary endpoint was a composite of all-cause death, hospitalization for heart failure, and fatal ventricular arrhythmia events. Patients were divided into three groups based on LVEF: preserved LVEF (≥50%, <i>n</i> = 251), moderately impai2025-01-01T00:00:00Z2025 Jan2025-04-04T03:06:01.382Z2025-04-04T03:06:01.382ZS-EPMC117201713980160210.1093/ehjopen/oeae100