{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["33(2)"],"submitter":["Mercadante V"],"pubmed_abstract":["<h4>Purpose</h4>This systematic review aimed to assess the updated literature for the prevention of salivary gland hypofunction and xerostomia induced by non-surgical cancer therapies.<h4>Methods</h4>Electronic databases of MEDLINE/PubMed, EMBASE, and Cochrane Library were searched for randomized controlled trials (RCT) that investigated interventions to prevent salivary gland hypofunction and/or xerostomia. Literature search began from the 2010 systematic review publications from the Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology (MASCC/ISOO) up to February 2024. Two independent reviewers extracted information regarding study design, study population, cancer treatment modality, interventions, outcome measures, methods, results, risk of bias ("],"journal":["Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer"],"pagination":["87"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11723892"],"repository":["biostudies-literature"],"pubmed_title":["A systematic review of salivary gland hypofunction and/or xerostomia induced by non-surgical cancer therapies: prevention strategies."],"pmcid":["PMC11723892"],"pubmed_authors":["Mercadante V","Clark H","Napenas JJ","Elad S","Kurup S","Wu J","Andabak-Rogulj A","Saunders DP","Peterson DE","Abdalla-Aslan R","Jaguar GC","Vissink A","Hovan A","Van Leeuwen S","Smith DK","Jensen SB","Brennan MT","Gueiros LA","Lynggaard CD","Fregnani ER","Laheij AMGA"],"additional_accession":[]},"is_claimable":false,"name":"A systematic review of salivary gland hypofunction and/or xerostomia induced by non-surgical cancer therapies: prevention strategies.","description":"<h4>Purpose</h4>This systematic review aimed to assess the updated literature for the prevention of salivary gland hypofunction and xerostomia induced by non-surgical cancer therapies.<h4>Methods</h4>Electronic databases of MEDLINE/PubMed, EMBASE, and Cochrane Library were searched for randomized controlled trials (RCT) that investigated interventions to prevent salivary gland hypofunction and/or xerostomia. Literature search began from the 2010 systematic review publications from the Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology (MASCC/ISOO) up to February 2024. Two independent reviewers extracted information regarding study design, study population, cancer treatment modality, interventions, outcome measures, methods, results, risk of bias (","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Jan","modification":"2026-06-02T07:15:24.068Z","creation":"2025-04-07T05:01:52.883Z"},"accession":"S-EPMC11723892","cross_references":{"pubmed":["39792256"],"doi":["10.1007/s00520-024-09113-x"]}}