biostudies-literatureUnknown13(24)Sulieman AMEThe arid mountainous region of Hail in Saudi Arabia has a variety of desert vegetation, some of which are conventionally used in Bedouin traditional medicine. These plants need scientific examination. This research seeks to examine <i>Blepharis ciliaris</i> using a thorough multi-analytical methodology that includes antibacterial and antioxidant assessments as well as computational modeling. GC-MS analysis of the methanolic extract revealed 17 organic compounds, including pentadecanoic acid, ethyl methyl ester (2.63%); hexadecanoic acid, methyl ester (1.00%); 9,12-octadecadienoic acid (Z,Z)-, methyl ester (2.74%); 9-octadecenoic acid, methyl ester (E) (2.78%); octadecanoic acid (5.88%); 9-tetradecenoic acid (Z) (3.22%); and undec-10-enoic acid, undec-2-n-1-yl ester (5.67%). The DPPH test ePlants (Basel, Switzerland)3491https://www.ebi.ac.uk/biostudies/studies/S-EPMC11728784biostudies-literatureComprehensive In Vitro Evaluation of Antibacterial, Antioxidant, and Computational Insights into <i>Blepharis ciliaris</i> (L.) B. L. Burtt from Hail Mountains, Saudi Arabia.PMC11728784Sulieman AMEIdriss HAlhudhaibi AMAlshammari MAlmuzaini NAMAlrushud HMAIbrahim NAAbdallah EMDahab MSaleh ZAfalseComprehensive In Vitro Evaluation of Antibacterial, Antioxidant, and Computational Insights into <i>Blepharis ciliaris</i> (L.) B. L. Burtt from Hail Mountains, Saudi Arabia.The arid mountainous region of Hail in Saudi Arabia has a variety of desert vegetation, some of which are conventionally used in Bedouin traditional medicine. These plants need scientific examination. This research seeks to examine <i>Blepharis ciliaris</i> using a thorough multi-analytical methodology that includes antibacterial and antioxidant assessments as well as computational modeling. GC-MS analysis of the methanolic extract revealed 17 organic compounds, including pentadecanoic acid, ethyl methyl ester (2.63%); hexadecanoic acid, methyl ester (1.00%); 9,12-octadecadienoic acid (Z,Z)-, methyl ester (2.74%); 9-octadecenoic acid, methyl ester (E) (2.78%); octadecanoic acid (5.88%); 9-tetradecenoic acid (Z) (3.22%); and undec-10-enoic acid, undec-2-n-1-yl ester (5.67%). The DPPH test e2024-01-01T00:00:00Z2024 Dec2026-04-15T03:26:00.84Z2025-04-04T08:29:48.991ZS-EPMC117287843977118910.3390/plants13243491