biostudies-literatureUnknown44(2)Nataprawira HM<h4>Background</h4>Data on childhood and adolescent multidrug/rifampicin-resistant tuberculosis (MDR/RR-TB) in Indonesia are lacking. We aimed to assess clinical features, adverse events (AEs) and treatment outcomes of childhood and adolescent MDR/RR-TB.<h4>Methods</h4>A retrospective cohort study was performed in children and adolescents <18 years old treated for MDR/RR-TB at Hasan Sadikin General Hospital in Bandung, Indonesia, between June 2016 and March 2024. Multivariable logistic regression analyses were used to calculate adjusted odds ratios (aOR) for predictors of all-cause mortality.<h4>Results</h4>Among 84 included patients, 69 (82%) were adolescents 10-17 years of age, 54 (64%) were female, 54 (64%) were malnourished and 55 (65%) had culture-confirmed disease. Among 69 (82%) patThe Pediatric infectious disease journal143-150https://www.ebi.ac.uk/biostudies/studies/S-EPMC11731024biostudies-literatureClinical Features, Adverse Events and Treatment Outcomes of Multidrug/Rifampicin-resistant Tuberculosis in Children and Adolescents: An Eight-year Retrospective Cohort Study in Bandung, Indonesia.PMC11731024Nataprawira HMRuslami RMenzies DGafar FSari CAAlffenaar JCMarais BJfalseClinical Features, Adverse Events and Treatment Outcomes of Multidrug/Rifampicin-resistant Tuberculosis in Children and Adolescents: An Eight-year Retrospective Cohort Study in Bandung, Indonesia.<h4>Background</h4>Data on childhood and adolescent multidrug/rifampicin-resistant tuberculosis (MDR/RR-TB) in Indonesia are lacking. We aimed to assess clinical features, adverse events (AEs) and treatment outcomes of childhood and adolescent MDR/RR-TB.<h4>Methods</h4>A retrospective cohort study was performed in children and adolescents <18 years old treated for MDR/RR-TB at Hasan Sadikin General Hospital in Bandung, Indonesia, between June 2016 and March 2024. Multivariable logistic regression analyses were used to calculate adjusted odds ratios (aOR) for predictors of all-cause mortality.<h4>Results</h4>Among 84 included patients, 69 (82%) were adolescents 10-17 years of age, 54 (64%) were female, 54 (64%) were malnourished and 55 (65%) had culture-confirmed disease. Among 69 (82%) pat2025-01-01T00:00:00Z2025 Feb2026-06-01T05:04:25.426Z2025-04-06T01:17:21.605ZS-EPMC117310243931263610.1097/INF.0000000000004539