{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Wong RJ"],"funding":["NCATS NIH HHS","NIDDK NIH HHS","NIA NIH HHS"],"pagination":["464-471"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11735693"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["59(5)"],"pubmed_abstract":["<h4>Goals and background</h4>Patients with cirrhosis undergoing liver transplant evaluation have high rates of pain and mental health comorbidities; both may significantly impair health-related quality of life (HRQL). We investigated the association between pain, anxiety/depression, and HRQL in this population.<h4>Study</h4>In 62 patients with cirrhosis undergoing liver transplant evaluation, we performed 4 validated assessments to characterize: pain (Brief Pain Inventory-Short Form, BPI-SF), anxiety (Generalized Anxiety Disorder-7), depression (Patient Health Questionnaire-8), and liver-specific HRQL (Chronic Liver Disease Questionnaire). The presence of pain was determined using the BPI-SF screening question. Linear regression was used to identify demographic or clinical factors predicti"],"journal":["Journal of clinical gastroenterology"],"pubmed_title":["The Complex Relationship Between Pain, Mental Health, and Quality-of-Life in Patients With Cirrhosis Undergoing Liver Transplant Evaluation."],"pmcid":["PMC11735693"],"funding_grant_id":["P30 DK026743","KL2 TR001870","R01 AG059183","K24 AG080021","K23 DK135901"],"pubmed_authors":["Stark Kent D","Wong RJ","Sharma A","Lai JC","Seal KH","Seetharaman S","Loeb R","Rubin JB","Barry F"],"additional_accession":[]},"is_claimable":false,"name":"The Complex Relationship Between Pain, Mental Health, and Quality-of-Life in Patients With Cirrhosis Undergoing Liver Transplant Evaluation.","description":"<h4>Goals and background</h4>Patients with cirrhosis undergoing liver transplant evaluation have high rates of pain and mental health comorbidities; both may significantly impair health-related quality of life (HRQL). We investigated the association between pain, anxiety/depression, and HRQL in this population.<h4>Study</h4>In 62 patients with cirrhosis undergoing liver transplant evaluation, we performed 4 validated assessments to characterize: pain (Brief Pain Inventory-Short Form, BPI-SF), anxiety (Generalized Anxiety Disorder-7), depression (Patient Health Questionnaire-8), and liver-specific HRQL (Chronic Liver Disease Questionnaire). The presence of pain was determined using the BPI-SF screening question. Linear regression was used to identify demographic or clinical factors predicti","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 May-Jun 01","modification":"2026-06-06T08:25:50.051Z","creation":"2026-05-27T03:12:10.449Z"},"accession":"S-EPMC11735693","cross_references":{"pubmed":["39008614"],"doi":["10.1097/mcg.0000000000002028","10.1097/MCG.0000000000002028"]}}