biostudies-literatureUnknown206(1)Jiang LDuring a fatal disease, patients often request updated information on their prognosis. After patients have already survived a certain time, conditional survival captures their future survival probability. We investigated conditional overall and failure-free survival in 473 younger mantle cell lymphoma (MCL) patients from a randomized phase III trial comparing immunochemotherapies R-CHOP and alternating R-CHOP/R-DHAP before autologous transplantation. Using conditional Kaplan-Meier method and Cox regression, we estimated subsequent survival of patients who had survived 1-8 years, considering MIPI, Ki-67, and treatment failure status. Starting at a lower level, R-CHOP patients only showed increasing subsequent survival as they survived longer (5-year conditional survival: 72% and 81% after sBritish journal of haematology159-166https://www.ebi.ac.uk/biostudies/studies/S-EPMC11739754biostudies-literatureConditional survival of younger patients with mantle cell lymphoma: Results from a randomized phase III trial of the European MCL Network.PMC11739754Hermine OJiang LWalewski JSchumacher MHoster EDreyling MThieblemont CPott CFeugier PHubel KRibrag VMansmann UBachy EfalseConditional survival of younger patients with mantle cell lymphoma: Results from a randomized phase III trial of the European MCL Network.During a fatal disease, patients often request updated information on their prognosis. After patients have already survived a certain time, conditional survival captures their future survival probability. We investigated conditional overall and failure-free survival in 473 younger mantle cell lymphoma (MCL) patients from a randomized phase III trial comparing immunochemotherapies R-CHOP and alternating R-CHOP/R-DHAP before autologous transplantation. Using conditional Kaplan-Meier method and Cox regression, we estimated subsequent survival of patients who had survived 1-8 years, considering MIPI, Ki-67, and treatment failure status. Starting at a lower level, R-CHOP patients only showed increasing subsequent survival as they survived longer (5-year conditional survival: 72% and 81% after s2025-01-01T00:00:00Z2025 Jan2026-06-02T04:30:47.31Z2026-04-14T03:13:21.611ZS-EPMC117397543944292110.1111/bjh.19854