biostudies-literatureUnknown11Gerras J<h4>Objective</h4>To describe the ocular findings, chronology of disease, and serum leptospiral titers in a group of horses, mules, and donkeys following an outbreak of leptospirosis.<h4>Methods</h4>Fifty Equidae in central North Carolina had ophthalmic examinations and serum leptospiral microscopic agglutination test (MAT) titers performed every 3-6 months for 24 months followed by a final examination at 34 months.<h4>Results</h4>Throughout the nearly three-year study period, 17 horses (34%; 17/49 horses) developed signs of uveitis; 20 eyes (20/34; 58.8%) of these 17 horses were visual at the initial examination, but only four eyes (11.8%) remained visual at the final examination. Serum titers (serogroups Pomona and Bratislava) in horses with uveitis were significantly elevated compared tFrontiers in veterinary science1504990https://www.ebi.ac.uk/biostudies/studies/S-EPMC11743373biostudies-literatureUveitis and blindness in a closed herd of Equidae following leptospiral infection.PMC11743373Salmon JHRoberts DWaldman GGilger BCYoung KGerras JfalseUveitis and blindness in a closed herd of Equidae following leptospiral infection.<h4>Objective</h4>To describe the ocular findings, chronology of disease, and serum leptospiral titers in a group of horses, mules, and donkeys following an outbreak of leptospirosis.<h4>Methods</h4>Fifty Equidae in central North Carolina had ophthalmic examinations and serum leptospiral microscopic agglutination test (MAT) titers performed every 3-6 months for 24 months followed by a final examination at 34 months.<h4>Results</h4>Throughout the nearly three-year study period, 17 horses (34%; 17/49 horses) developed signs of uveitis; 20 eyes (20/34; 58.8%) of these 17 horses were visual at the initial examination, but only four eyes (11.8%) remained visual at the final examination. Serum titers (serogroups Pomona and Bratislava) in horses with uveitis were significantly elevated compared t2024-01-01T00:00:00Z20242025-04-25T18:48:55.712Z2025-04-06T07:42:07.106ZS-EPMC117433733983492210.3389/fvets.2024.1504990