{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Sato Folatre JG"],"funding":["The Local Research and Development Council Fyrbodal","Helicopter Emergency Medical Service, Region Västra Götaland","The Centre for Disaster Medicine, Gothenburg University","The Swedish Armed Forces Science & Technology Fund","The Department of Haematology and Coagulation Disorders","The Swedish Society for Military Medical Officers"],"pagination":["e14568"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11744058"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["69(2)"],"pubmed_abstract":["<h4>Background</h4>Haemorrhage is a leading cause of morbidity and mortality in trauma, and prehospital transfusion of blood products is often necessary. Whole blood has been proposed to be the best alternative, but it is unclear whether, and how, storage and transport of the blood in a helicopter affects the blood units. We investigated the coagulation capacity and platelet function in whole blood at different time points during helicopter missions.<h4>Methods</h4>Twenty units of low-titre group O RhD negative whole blood were collected from healthy volunteers and analysed before, during and after transport in a helicopter. Coagulation and platelet function, as measured by thromboelastography, and blood samples for pH, electrolytes, glucose and lactate were assessed at baseline and 24, 72"],"journal":["Acta anaesthesiologica Scandinavica"],"pubmed_title":["Coagulation and platelet function in cold-stored whole blood on missions in a helicopter emergency service."],"pmcid":["PMC11744058"],"funding_grant_id":["AT9221011"],"pubmed_authors":["Arnell P","Sandstrom G","Romlin B","Sato Folatre JG","Radulovic V","Skallsjo G","Wikman A","Ricksten SE"],"additional_accession":[]},"is_claimable":false,"name":"Coagulation and platelet function in cold-stored whole blood on missions in a helicopter emergency service.","description":"<h4>Background</h4>Haemorrhage is a leading cause of morbidity and mortality in trauma, and prehospital transfusion of blood products is often necessary. Whole blood has been proposed to be the best alternative, but it is unclear whether, and how, storage and transport of the blood in a helicopter affects the blood units. We investigated the coagulation capacity and platelet function in whole blood at different time points during helicopter missions.<h4>Methods</h4>Twenty units of low-titre group O RhD negative whole blood were collected from healthy volunteers and analysed before, during and after transport in a helicopter. Coagulation and platelet function, as measured by thromboelastography, and blood samples for pH, electrolytes, glucose and lactate were assessed at baseline and 24, 72","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Feb","modification":"2025-04-03T23:58:12.401Z","creation":"2025-04-03T23:58:12.401Z"},"accession":"S-EPMC11744058","cross_references":{"pubmed":["39829054"],"doi":["10.1111/aas.14568"]}}