{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Modha S"],"funding":["Medical Research Council"],"pagination":["veaf002"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11749082"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["11(1)"],"pubmed_abstract":["Anelloviruses are a group of small, circular, single-stranded DNA viruses that are found ubiquitously across mammalian hosts. Here, we explored a large number of publicly available human microbiome datasets and retrieved a total of 829 anellovirus genomes, substantially expanding the known diversity of these viruses. The majority of new genomes fall within the three major human anellovirus genera: <i>Alphatorquevirus, Betatorquevirus</i>, and <i>Gammatorquevirus</i>, while we also present new genomes of the under-sampled <i>Hetorquevirus, Memtorquevirus</i>, and <i>Samektorquevirus</i> genera. We performed recombination analysis and show evidence of extensive recombination across all human anelloviruses. Interestingly, more than 95% of the detected events are between members of the same ge"],"journal":["Virus evolution"],"pubmed_title":["Expanding the genomic diversity of human anelloviruses."],"pmcid":["PMC11749082"],"funding_grant_id":["MC_UU_1201412 MR/S502479/1"],"pubmed_authors":["Lytras S","Modha S","Hughes J","Orton RJ"],"additional_accession":[]},"is_claimable":false,"name":"Expanding the genomic diversity of human anelloviruses.","description":"Anelloviruses are a group of small, circular, single-stranded DNA viruses that are found ubiquitously across mammalian hosts. Here, we explored a large number of publicly available human microbiome datasets and retrieved a total of 829 anellovirus genomes, substantially expanding the known diversity of these viruses. The majority of new genomes fall within the three major human anellovirus genera: <i>Alphatorquevirus, Betatorquevirus</i>, and <i>Gammatorquevirus</i>, while we also present new genomes of the under-sampled <i>Hetorquevirus, Memtorquevirus</i>, and <i>Samektorquevirus</i> genera. We performed recombination analysis and show evidence of extensive recombination across all human anelloviruses. Interestingly, more than 95% of the detected events are between members of the same ge","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025","modification":"2026-04-08T19:05:55.836Z","creation":"2025-04-07T07:50:17.848Z"},"accession":"S-EPMC11749082","cross_references":{"pubmed":["39839678"],"doi":["10.1093/ve/veaf002"]}}