{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhou H"],"funding":["National Key R&D Program of China"],"pagination":["262"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11758629"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["15(2)"],"pubmed_abstract":["Penaeid shrimp, with its genomes enriched in short tandem repeats (STRs), presents an ideal model for studying the distribution and biological functions of STRs. In this study, we systematically identified and compared STRs across multiple species, confirming a significantly higher prevalence of STRs (26-32%) in penaeid shrimp, which is markedly higher than that observed in other species, such as mammals (1.3-2.1%) and plants (0.21-0.73%). Further analysis utilizing a cohort of 326 Pacific white shrimp revealed a total of 672,507 high-quality STRs evenly distributed across the genome, with a notably lower frequency of SNPs within these STR regions. Focusing on growth traits as a case study, we conducted a genome-wide association study (GWAS) and correlation analyses to identify the regulat"],"journal":["Animals : an open access journal from MDPI"],"pubmed_title":["Copy Number Variations in Short Tandem Repeats Modulate Growth Traits in Penaeid Shrimp Through Neighboring Gene Regulation."],"pmcid":["PMC11758629"],"funding_grant_id":["2022YFD2400202"],"pubmed_authors":["Xia Y","Fu Q","Liu M","Tan J","Chen M","Luan S","Kong J","Chen B","Meng X","Li X","Luo K","Dai P","Qiang G","Sui J","Zhou H","Xing Q"],"additional_accession":[]},"is_claimable":false,"name":"Copy Number Variations in Short Tandem Repeats Modulate Growth Traits in Penaeid Shrimp Through Neighboring Gene Regulation.","description":"Penaeid shrimp, with its genomes enriched in short tandem repeats (STRs), presents an ideal model for studying the distribution and biological functions of STRs. In this study, we systematically identified and compared STRs across multiple species, confirming a significantly higher prevalence of STRs (26-32%) in penaeid shrimp, which is markedly higher than that observed in other species, such as mammals (1.3-2.1%) and plants (0.21-0.73%). Further analysis utilizing a cohort of 326 Pacific white shrimp revealed a total of 672,507 high-quality STRs evenly distributed across the genome, with a notably lower frequency of SNPs within these STR regions. Focusing on growth traits as a case study, we conducted a genome-wide association study (GWAS) and correlation analyses to identify the regulat","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Jan","modification":"2025-04-18T12:46:03.823Z","creation":"2025-04-06T22:06:57.961Z"},"accession":"S-EPMC11758629","cross_references":{"pubmed":["39858262"],"doi":["10.3390/ani15020262"]}}