biostudies-literatureUnknown64(2)Vazquez-Ruiz ZUniversidad de NavarraPlant-based dietary patterns have been demonstrated to reduce the risk of non-communicable disease (NCD), including cardiovascular disease (CVD), type 2 diabetes, cancer, and all-cause mortality. Phenolic compounds (PC), abundant in plant-based foods, have been considered as instrumental in this attenuation of NCD risk. We evaluated the association between dietary intake of PC and the risk of all-cause mortality in a relatively young Mediterranean cohort of 18,173 Spanish participants in the "Seguimiento Universidad de Navarra" (SUN) project, after a median follow-up of 12.7 years. Intake of PC was estimated at baseline and repeatedly after 10-year follow-up using a 136-item validated food frequency questionnaire and the Phenol-Explorer database. During 236,329 person-years, 544 deaths werEuropean journal of nutrition70https://www.ebi.ac.uk/biostudies/studies/S-EPMC11761832biostudies-literatureEffect of dietary phenolic compounds intake on mortality in the "Seguimiento Universidad De Navarra" (SUN) Mediterranean cohort.PMC11761832Toledo EVazquez-Ruiz ZBes-Rastrollo MMartinez-Gonzalez MAVitelli-Storelli FfalseEffect of dietary phenolic compounds intake on mortality in the "Seguimiento Universidad De Navarra" (SUN) Mediterranean cohort.Plant-based dietary patterns have been demonstrated to reduce the risk of non-communicable disease (NCD), including cardiovascular disease (CVD), type 2 diabetes, cancer, and all-cause mortality. Phenolic compounds (PC), abundant in plant-based foods, have been considered as instrumental in this attenuation of NCD risk. We evaluated the association between dietary intake of PC and the risk of all-cause mortality in a relatively young Mediterranean cohort of 18,173 Spanish participants in the "Seguimiento Universidad de Navarra" (SUN) project, after a median follow-up of 12.7 years. Intake of PC was estimated at baseline and repeatedly after 10-year follow-up using a 136-item validated food frequency questionnaire and the Phenol-Explorer database. During 236,329 person-years, 544 deaths wer2025-01-01T00:00:00Z2025 Jan2025-04-04T13:11:41.965Z2025-04-04T13:11:41.965ZS-EPMC117618323985342510.1007/s00394-025-03581-5