{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Kuang X"],"funding":["Scientific Research Fund of Hunan Provincial Education Department","Natural Science Foundation of Hunan Province","National Natural Science Foundation of China","National Key Research and Development Program of China"],"pagination":["57"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11762372"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(1)"],"pubmed_abstract":["Plants frequently encounter relatively low and fluctuating potassium (K<sup>+</sup>) concentrations in soil, with roots serving as primary responders to this stress. Histone modifications, such as de-/acetylation, can function as epigenetic markers of stress-inducible genes. However, the signaling network between histone modifications and low-K<sup>+</sup> (LK) response pathways remains unclear. This study investigated the regulatory role of Histone Deacetylase Complex 1 (HDC1) in primary root growth of <i>Arabidopsis thaliana</i> under K<sup>+</sup> deficiency stress. Using a <i>hdc1-2</i> mutant line, we observed that HDC1 positively regulated root growth under LK conditions. Compared to wild-type (WT) plants, the <i>hdc1-2</i> mutant exhibited significantly inhibited primary root growth"],"journal":["Biology"],"pubmed_title":["HDC1 Promotes Primary Root Elongation by Regulating Auxin and K&lt;sup&gt;+&lt;/sup&gt; Homeostasis in Response to Low-K&lt;sup&gt;+&lt;/sup&gt; Stress."],"pmcid":["PMC11762372"],"funding_grant_id":["30900099","2024JJ5196","2018YFD1000404","23A0189"],"pubmed_authors":["Huang C","Wang R","Huang Z","Xiang J","Zeng J","Lin W","Liu Q","Chen H","Kuang X","Su Y"],"additional_accession":[]},"is_claimable":false,"name":"HDC1 Promotes Primary Root Elongation by Regulating Auxin and K&lt;sup&gt;+&lt;/sup&gt; Homeostasis in Response to Low-K&lt;sup&gt;+&lt;/sup&gt; Stress.","description":"Plants frequently encounter relatively low and fluctuating potassium (K<sup>+</sup>) concentrations in soil, with roots serving as primary responders to this stress. Histone modifications, such as de-/acetylation, can function as epigenetic markers of stress-inducible genes. However, the signaling network between histone modifications and low-K<sup>+</sup> (LK) response pathways remains unclear. This study investigated the regulatory role of Histone Deacetylase Complex 1 (HDC1) in primary root growth of <i>Arabidopsis thaliana</i> under K<sup>+</sup> deficiency stress. Using a <i>hdc1-2</i> mutant line, we observed that HDC1 positively regulated root growth under LK conditions. Compared to wild-type (WT) plants, the <i>hdc1-2</i> mutant exhibited significantly inhibited primary root growth","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Jan","modification":"2025-04-04T11:46:19.661Z","creation":"2025-04-04T11:46:19.661Z"},"accession":"S-EPMC11762372","cross_references":{"pubmed":["39857288"],"doi":["10.3390/biology14010057"]}}