{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["74(1)"],"submitter":["Reina-Couto M"],"funding":["Universidade do Porto"],"pubmed_abstract":["<h4>Background and aims</h4>Endocan has been scarcely explored in COVID-19, especially regarding its modulation by veno-venous extracorporeal membrane oxygenation (VV-ECMO), hypertension or previous renin-angiotensin-aldosterone system (RAAS) inhibitors treatment. We compared endocan and other endotheliitis markers in hospitalized COVID-19 patients and assessed their modulation by VV-ECMO, hypertension and previous RAAS inhibitors treatment.<h4>Material and methods</h4>Serum endocan, intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1) and E-selectin were measured in \"severe\" (n = 27), \"critically ill\" (n = 17) and \"critically ill on VV-ECMO\" (n = 17) COVID-19 patients at admission, days 3-4, 5-8 and weekly thereafter, and in controls (n = 23) at a single "],"journal":["Inflammation research : official journal of the European Histamine Research Society ... [et al.]"],"pagination":["26"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11762693"],"repository":["biostudies-literature"],"pubmed_title":["Endocan as a marker of endotheliitis in COVID-19 patients: modulation by veno-venous extracorporeal membrane oxygenation, arterial hypertension and previous treatment with renin-angiotensin-aldosterone system inhibitors."],"pmcid":["PMC11762693"],"pubmed_authors":["Pereira-Terra P","Sarmento A","Paiva JA","Dias CC","Silva-Pereira C","Sousa T","Martins S","Albino-Teixeira A","Guimaraes JT","Roncon-Albuquerque R","Reina-Couto M","Alves D","Tavares M","Bessa J","Teixeira-Santos L","Morato M","Pinho D"],"additional_accession":[]},"is_claimable":false,"name":"Endocan as a marker of endotheliitis in COVID-19 patients: modulation by veno-venous extracorporeal membrane oxygenation, arterial hypertension and previous treatment with renin-angiotensin-aldosterone system inhibitors.","description":"<h4>Background and aims</h4>Endocan has been scarcely explored in COVID-19, especially regarding its modulation by veno-venous extracorporeal membrane oxygenation (VV-ECMO), hypertension or previous renin-angiotensin-aldosterone system (RAAS) inhibitors treatment. We compared endocan and other endotheliitis markers in hospitalized COVID-19 patients and assessed their modulation by VV-ECMO, hypertension and previous RAAS inhibitors treatment.<h4>Material and methods</h4>Serum endocan, intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1) and E-selectin were measured in \"severe\" (n = 27), \"critically ill\" (n = 17) and \"critically ill on VV-ECMO\" (n = 17) COVID-19 patients at admission, days 3-4, 5-8 and weekly thereafter, and in controls (n = 23) at a single ","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Jan","modification":"2026-06-12T05:15:55.921Z","creation":"2025-04-03T23:22:38.405Z"},"accession":"S-EPMC11762693","cross_references":{"pubmed":["39862311"],"doi":["10.1007/s00011-024-01964-8"]}}