biostudies-literatureYao YNatural Science Foundation of Jiangxi ProvinceNational Natural Science Foundation of China22https://www.ebi.ac.uk/biostudies/studies/S-EPMC11762907biostudies-literatureUnknown23(1)<h4>Purpose</h4>This study aimed to determine the optimal natural orifice specimen extraction (NOSE) method for robotic-assisted mid-rectal cancer resection in women.<h4>Methods</h4>This retrospective propensity score-matched (PSM) study was to analyze the clinical data prospectively collected from female rectal cancer patients who underwent either robotic-assisted transvaginal specimen extraction (RATV) or robotic-assisted transanal specimen extraction (RATA) at our center between June 2016 and December 2022. The main outcome measures were urinary, anal, and sexual function. Disease-free survival (DFS), and overall survival (OS) were also included .<h4>Results</h4>Anal function, assessed by the Wexner score, was better in the RATV group than in the RATA group (P = 0.034). Additionally, prWorld journal of surgical oncologyEfficacy comparison of optimal natural orifice specimen extraction for robotic middle rectal cancer resection in women: transanal or transvaginal orifice.PMC1176290720202BABL20608282160561Ju HLiu YYao YYang LLi TLiang YLei XDing JYuan YfalseEfficacy comparison of optimal natural orifice specimen extraction for robotic middle rectal cancer resection in women: transanal or transvaginal orifice.<h4>Purpose</h4>This study aimed to determine the optimal natural orifice specimen extraction (NOSE) method for robotic-assisted mid-rectal cancer resection in women.<h4>Methods</h4>This retrospective propensity score-matched (PSM) study was to analyze the clinical data prospectively collected from female rectal cancer patients who underwent either robotic-assisted transvaginal specimen extraction (RATV) or robotic-assisted transanal specimen extraction (RATA) at our center between June 2016 and December 2022. The main outcome measures were urinary, anal, and sexual function. Disease-free survival (DFS), and overall survival (OS) were also included .<h4>Results</h4>Anal function, assessed by the Wexner score, was better in the RATV group than in the RATA group (P = 0.034). Additionally, pr2025-01-01T00:00:00Z2025 Jan2025-04-05T11:34:38.454Z2025-04-05T11:34:38.454ZS-EPMC117629073985673110.1186/s12957-024-03630-z