biostudies-literatureUnknown15(1)Krug N<b>Background/Objectives:</b> The p48 MW HPC is a novel low-profile flow diverter covered by a hydrophilic polymer coating with antithrombogenic properties, which may reduce ischemic complications and enable a single antiplatelet therapy after insertion of the stent. In this single-center experience, we describe the efficacy of this device, focusing on the illustration of different therapeutic indications and the outcome in various clinical settings with regard to vessel anatomy, bleeding state, and aneurysm configuration. <b>Methods:</b> We retrospectively reviewed our database for all patients being treated with a p48 MW HPC flow diverter between February 2019 and July 2021. The efficacy of the treatment was evaluated according to the O'Kelly-Marotta (OKM) scale in the last digital subtrBrain sciences42https://www.ebi.ac.uk/biostudies/studies/S-EPMC11763383biostudies-literatureIntracranial Aneurysms Treated with a Novel Coated Low-Profile Flow Diverter (p48 HPC)-A Single-Center Experience and an Illustrative Case Series.PMC11763383Sepp DMeyer BAlbrecht CWostrack MMaegerlein CBoeckh-Behrens TKirschke JSKreiser KZimmer CKrug NfalseIntracranial Aneurysms Treated with a Novel Coated Low-Profile Flow Diverter (p48 HPC)-A Single-Center Experience and an Illustrative Case Series.<b>Background/Objectives:</b> The p48 MW HPC is a novel low-profile flow diverter covered by a hydrophilic polymer coating with antithrombogenic properties, which may reduce ischemic complications and enable a single antiplatelet therapy after insertion of the stent. In this single-center experience, we describe the efficacy of this device, focusing on the illustration of different therapeutic indications and the outcome in various clinical settings with regard to vessel anatomy, bleeding state, and aneurysm configuration. <b>Methods:</b> We retrospectively reviewed our database for all patients being treated with a p48 MW HPC flow diverter between February 2019 and July 2021. The efficacy of the treatment was evaluated according to the O'Kelly-Marotta (OKM) scale in the last digital subtr2025-01-01T00:00:00Z2025 Jan2025-04-18T14:28:15.794Z2025-04-07T00:39:22.921ZS-EPMC117633833985141010.3390/brainsci15010042