biostudies-literatureHuang JNatural Science Foundation of Fujian ProvinceSeed Industry Innovation and Industrialization in Fujian ProvinceMinjiang University Introduces Talent pre-research project65https://www.ebi.ac.uk/biostudies/studies/S-EPMC11764893biostudies-literatureUnknown16(1)(1) Background: Animal growth is a complex process, involving the coordination of a wide variety of genes, non-coding RNAs, and pathways. Circular RNAs (circRNAs) belong to a novel class of functional non-coding RNAs (ncRNAs). They have a distinctive ring structure and are involved in various biological processes, including the proliferation, differentiation, and apoptosis of muscle cells. The Pacific abalone <i>Haliotis discus hannai</i> is an economically valuable mollusk species cultivated in China. However, the modulation of muscle growth by circRNAs in this species is poorly understood. (2) Methods: In this study, we analyzed the muscle transcriptomes of 6 <i>H. discus hannai</i> specimens: three small (S_HD) and three large (L_HD) groups via RNA-seq and bioinformatics technology. (3)GenesTranscriptome Analysis of Muscle Growth-Related circRNA in the Pacific Abalone &lt;i&gt;Haliotis discus hanna&lt;/i&gt;.PMC11764893MJY220082021FJSCZY022022J011137MJY24020Zhou MHuang JHe JLi DChen JShe ZKe CfalseTranscriptome Analysis of Muscle Growth-Related circRNA in the Pacific Abalone &lt;i&gt;Haliotis discus hanna&lt;/i&gt;.(1) Background: Animal growth is a complex process, involving the coordination of a wide variety of genes, non-coding RNAs, and pathways. Circular RNAs (circRNAs) belong to a novel class of functional non-coding RNAs (ncRNAs). They have a distinctive ring structure and are involved in various biological processes, including the proliferation, differentiation, and apoptosis of muscle cells. The Pacific abalone <i>Haliotis discus hannai</i> is an economically valuable mollusk species cultivated in China. However, the modulation of muscle growth by circRNAs in this species is poorly understood. (2) Methods: In this study, we analyzed the muscle transcriptomes of 6 <i>H. discus hannai</i> specimens: three small (S_HD) and three large (L_HD) groups via RNA-seq and bioinformatics technology. (3)2025-01-01T00:00:00Z2025 Jan2026-04-18T03:27:34.501Z2025-04-07T00:36:38.443ZS-EPMC117648933985861210.3390/genes16010065