{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Bian X"],"funding":["Chinese Academy of Tropical Agricultural Sciences for Science and Technology Innovation Team of National Tropical Agricultural Science Center","Project of National Key Laboratory for Tropical Crop Breeding","National Key Laboratory for Tropical Crop Breeding","Hainan Provincial Natural Science Foundation of China","Nanhai New Star Technology Innovation Talent Platform Project of Hainan Province","Chinese Academy of Tropical Agricultural Sciences for Science and Technology Innovation Team of the National Tropical Agricultural Science Center"],"pagination":["798"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11765665"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["26(2)"],"pubmed_abstract":["The biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), which are essential for sesquiterpenes and triterpenes, respectively, is primarily governed by the mevalonate pathway, wherein <i>farnesyl pyrophosphate synthase</i> (<i>FPS</i>) plays a pivotal role. This study identified eight members of the FPS gene family in <i>Euphorbia hirta</i>, designated <i>EhFPS1</i>-<i>EhFPS8</i>, through bioinformatics analysis, revealing their distribution across several chromosomes and a notable tandem gene cluster. The genes exhibited strong hydrophilic properties and key functional motifs crucial for enzyme activity. An in-depth analysis of the <i>EhFPS</i> genes highlighted their significant involvement in isoprenoid metabolism and lipid biosynthesis, with expression p"],"journal":["International journal of molecular sciences"],"pubmed_title":["Genome-Wide Identification and Expression Profile of &lt;i&gt;Farnesyl Pyrophosphate Synthase&lt;/i&gt; (&lt;i&gt;FPS&lt;/i&gt;) Gene Family in &lt;i&gt;Euphorbia Hirta&lt;/i&gt; L."],"pmcid":["PMC11765665"],"funding_grant_id":["NKLTCBCXTD01","NHXXRCXM202330","324QN304","CATASCXTD202401"],"pubmed_authors":["Han Q","Qiang R","Xu D","Wang H","Rehman F","Deng Z","An Z","Bian X","Wu T","Wang X","Wu W","Cheng H","Yuan Y"],"additional_accession":[]},"is_claimable":false,"name":"Genome-Wide Identification and Expression Profile of &lt;i&gt;Farnesyl Pyrophosphate Synthase&lt;/i&gt; (&lt;i&gt;FPS&lt;/i&gt;) Gene Family in &lt;i&gt;Euphorbia Hirta&lt;/i&gt; L.","description":"The biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), which are essential for sesquiterpenes and triterpenes, respectively, is primarily governed by the mevalonate pathway, wherein <i>farnesyl pyrophosphate synthase</i> (<i>FPS</i>) plays a pivotal role. This study identified eight members of the FPS gene family in <i>Euphorbia hirta</i>, designated <i>EhFPS1</i>-<i>EhFPS8</i>, through bioinformatics analysis, revealing their distribution across several chromosomes and a notable tandem gene cluster. The genes exhibited strong hydrophilic properties and key functional motifs crucial for enzyme activity. An in-depth analysis of the <i>EhFPS</i> genes highlighted their significant involvement in isoprenoid metabolism and lipid biosynthesis, with expression p","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Jan","modification":"2026-04-18T03:21:11.899Z","creation":"2025-04-19T18:23:59.923Z"},"accession":"S-EPMC11765665","cross_references":{"pubmed":["39859518"],"doi":["10.3390/ijms26020798"]}}