{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Traversa D"],"funding":["ELIXIRNextGenIT"],"pagination":["137"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11767486"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["13(1)"],"pubmed_abstract":["Polyhydroxybutyrate (PHB) is a biodegradable natural polymer produced by different prokaryotes as a valuable carbon and energy storage compound. Its biosynthesis pathway requires the sole expression of the <i>phaCAB</i> operon, although auxiliary genes play a role in controlling polymer accumulation, degradation, granule formation and stabilization. Due to its biodegradability, PHB is currently regarded as a promising alternative to synthetic plastics for industrial/biotechnological applications. <i>Azohydromonas lata</i> strain H1 has been reported to accumulate PHB by using simple, inexpensive carbon sources. Here, we present the first de novo genome assembly of the <i>A. lata</i> strain H1. The genome assembly is over 7.7 Mb in size, including a circular megaplasmid of approximately 456"],"journal":["Microorganisms"],"pubmed_title":["De Novo Assembly of the Polyhydroxybutyrate (PHB) Producer <i>Azohydromonas lata</i> Strain H1 Genome and Genomic Analysis of PHB Production Machinery."],"pmcid":["PMC11767486"],"funding_grant_id":["IR0000010"],"pubmed_authors":["Calia C","Pazzani C","Traversa D","Chimienti G","Manzari C","Pesole G","D'Addabbo P","Oliva M","Mandorino C","Chiara M","Marzella A","Trisolini L","Scrascia M"],"additional_accession":[]},"is_claimable":false,"name":"De Novo Assembly of the Polyhydroxybutyrate (PHB) Producer <i>Azohydromonas lata</i> Strain H1 Genome and Genomic Analysis of PHB Production Machinery.","description":"Polyhydroxybutyrate (PHB) is a biodegradable natural polymer produced by different prokaryotes as a valuable carbon and energy storage compound. Its biosynthesis pathway requires the sole expression of the <i>phaCAB</i> operon, although auxiliary genes play a role in controlling polymer accumulation, degradation, granule formation and stabilization. Due to its biodegradability, PHB is currently regarded as a promising alternative to synthetic plastics for industrial/biotechnological applications. <i>Azohydromonas lata</i> strain H1 has been reported to accumulate PHB by using simple, inexpensive carbon sources. Here, we present the first de novo genome assembly of the <i>A. lata</i> strain H1. The genome assembly is over 7.7 Mb in size, including a circular megaplasmid of approximately 456","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Jan","modification":"2026-05-23T03:21:49.333Z","creation":"2025-04-04T20:56:53.957Z"},"accession":"S-EPMC11767486","cross_references":{"pubmed":["39858905"],"doi":["10.3390/microorganisms13010137"]}}