{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhang Y"],"funding":["the Taizhou Science and Technology Plan Project","National College Students' Innovation and Entrepreneurship Training Program","the Jiangxi Province Key Laboratory of Functional Crystalline Materials Chemistry","the Key Research and Development Project of Hainan Province","the National Key R&D Program of China","the Education Department of Jiangxi Province","the National Natural Science Foundation of China"],"pagination":["407"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11768993"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["25(2)"],"pubmed_abstract":["The detection of highly toxic chemicals such as phosgene is crucial for addressing the severe threats to human health and public safety posed by terrorist attacks and industrial mishaps. However, timely and precise monitoring of phosgene at a low cost remains a significant challenge. This work is the first to report a novel fluorescent system based on the Intramolecular Charge Transfer (ICT) effect, which can rapidly detect phosgene in both solution and gas phases with high sensitivity by integrating a benzo[1,2-b:6,5-b']dithiophene-4,5-diamine (BDTA) probe. Among existing detecting methods, this fluorescent system stands out as it can respond to phosgene within a mere 30 s and has a detection limit as low as 0.16 μM in solution. Furthermore, the sensing mechanism was rigorously validated "],"journal":["Sensors (Basel, Switzerland)"],"pubmed_title":["Benzo[1,2-b:6,5-b']dithiophene-4,5-diamine: A New Fluorescent Probe for the High-Sensitivity and Real-Time Visual Monitoring of Phosgene."],"pmcid":["PMC11768993"],"funding_grant_id":["ZDYF2024GXJS019","No.GJJ2200820","202110407006","2023YFC2908100","No. 23gya18","2024SSY05161","No. 52463014"],"pubmed_authors":["Liu Z","Liu K","Ma C","Zhang Y","Xiao J","Peng R","Feng X","Mao H"],"additional_accession":[]},"is_claimable":false,"name":"Benzo[1,2-b:6,5-b']dithiophene-4,5-diamine: A New Fluorescent Probe for the High-Sensitivity and Real-Time Visual Monitoring of Phosgene.","description":"The detection of highly toxic chemicals such as phosgene is crucial for addressing the severe threats to human health and public safety posed by terrorist attacks and industrial mishaps. However, timely and precise monitoring of phosgene at a low cost remains a significant challenge. This work is the first to report a novel fluorescent system based on the Intramolecular Charge Transfer (ICT) effect, which can rapidly detect phosgene in both solution and gas phases with high sensitivity by integrating a benzo[1,2-b:6,5-b']dithiophene-4,5-diamine (BDTA) probe. Among existing detecting methods, this fluorescent system stands out as it can respond to phosgene within a mere 30 s and has a detection limit as low as 0.16 μM in solution. Furthermore, the sensing mechanism was rigorously validated ","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Jan","modification":"2025-04-25T18:53:41.477Z","creation":"2025-04-06T07:45:32.244Z"},"accession":"S-EPMC11768993","cross_references":{"pubmed":["39860777"],"doi":["10.3390/s25020407"]}}