{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["46(2)"],"submitter":["Kelani H"],"pubmed_abstract":["<h4>Background</h4>Early neurological deterioration (END) and recurrence of vessel blockage frequently complicate intravenous thrombolysis (IVT) for acute ischemic stroke (AIS). Several studies have indicated the potential effectiveness of the early initiation (within < 24 h) of antiplatelet therapy (APT) after IVT. However, conflicting results have been reported by other studies. We aimed to offer a thorough overview of the current literature through a systematic review and meta-analysis.<h4>Methods</h4>Our systematic review and meta-analysis were prospectively registered on PROSPERO (ID: CRD42023488173) following the PRISMA guidelines. We systematically searched Web of Science, SCOPUS, PubMed, and Cochrane Library until May 5, 2024. Rayyan. ai facilitated the screening process. The R sta"],"journal":["Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology"],"pagination":["617-631"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11772446"],"repository":["biostudies-literature"],"pubmed_title":["Early antiplatelet therapy after intravenous thrombolysis for acute ischemic stroke: a systematic review and meta-analysis."],"pmcid":["PMC11772446"],"pubmed_authors":["Albaramony N","Al-Mufti F","Berekashvili K","Kay AD","Abdelazeem A","Lerner DP","El-Ghanem M","Kelani H","Naeem A","Greene-Chandos D","Abuelazm M","Elhalag RH","Merlin LR","Tiwari A","Quinoa TR"],"additional_accession":[]},"is_claimable":false,"name":"Early antiplatelet therapy after intravenous thrombolysis for acute ischemic stroke: a systematic review and meta-analysis.","description":"<h4>Background</h4>Early neurological deterioration (END) and recurrence of vessel blockage frequently complicate intravenous thrombolysis (IVT) for acute ischemic stroke (AIS). Several studies have indicated the potential effectiveness of the early initiation (within < 24 h) of antiplatelet therapy (APT) after IVT. However, conflicting results have been reported by other studies. We aimed to offer a thorough overview of the current literature through a systematic review and meta-analysis.<h4>Methods</h4>Our systematic review and meta-analysis were prospectively registered on PROSPERO (ID: CRD42023488173) following the PRISMA guidelines. We systematically searched Web of Science, SCOPUS, PubMed, and Cochrane Library until May 5, 2024. Rayyan. ai facilitated the screening process. The R sta","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Feb","modification":"2025-04-04T20:56:56.945Z","creation":"2025-04-04T20:56:56.945Z"},"accession":"S-EPMC11772446","cross_references":{"pubmed":["39470903"],"doi":["10.1007/s10072-024-07821-0"]}}