{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["14"],"submitter":["Yu C"],"pubmed_abstract":["<h4>Objectives</h4>This study aimed to estimate the incidence of norovirus (NoV)-associated diarrhea and asymptomatic infections in children under 4 years of age and identify the genotypes of multiple NoV infections.<h4>Methods</h4>A community-based cohort study was conducted in Tarlac, Philippines. Children aged 0-2 years were followed up for 2 years. The prevalence and incidence rates of NoV-associated diarrhea and asymptomatic infections were calculated. Risk factors were assessed using the Cox proportional hazards model. The genotypes and immunotypes of repeated infections were tabulated.<h4>Results</h4>A total of 338 children aged 6208 child-months were analyzed. NoV was detected in 17.4% (84 of 527, 95% confidence interval [CI]: 12.7-19.7%) of diarrheal episodes and 10.8% (219 of 203"],"journal":["IJID regions"],"pagination":["100549"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11773203"],"repository":["biostudies-literature"],"pubmed_title":["Norovirus-associated diarrhea and asymptomatic infection in children aged under 4 years: a community-cohort study in the Philippines."],"pmcid":["PMC11773203"],"pubmed_authors":["Sayama Y","Okamoto M","Yu C","Saito-Obata M","Kishi M","Corpuz MCA","Bonifacio JM","Oshitani H","Saito M","Dapat C","Imamura T"],"additional_accession":[]},"is_claimable":false,"name":"Norovirus-associated diarrhea and asymptomatic infection in children aged under 4 years: a community-cohort study in the Philippines.","description":"<h4>Objectives</h4>This study aimed to estimate the incidence of norovirus (NoV)-associated diarrhea and asymptomatic infections in children under 4 years of age and identify the genotypes of multiple NoV infections.<h4>Methods</h4>A community-based cohort study was conducted in Tarlac, Philippines. Children aged 0-2 years were followed up for 2 years. The prevalence and incidence rates of NoV-associated diarrhea and asymptomatic infections were calculated. Risk factors were assessed using the Cox proportional hazards model. The genotypes and immunotypes of repeated infections were tabulated.<h4>Results</h4>A total of 338 children aged 6208 child-months were analyzed. NoV was detected in 17.4% (84 of 527, 95% confidence interval [CI]: 12.7-19.7%) of diarrheal episodes and 10.8% (219 of 203","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Mar","modification":"2025-04-04T23:12:12.214Z","creation":"2025-04-04T23:12:12.214Z"},"accession":"S-EPMC11773203","cross_references":{"pubmed":["39877416"],"doi":["10.1016/j.ijregi.2024.100549"]}}