biostudies-literatureUnknown5(1)Ding D<h4>Background</h4>Coronary physiology measured by fractional flow reserve (FFR) is superior to angiography for assessing the efficacy of percutaneous coronary intervention (PCI). Yet, the clinical adoption of post-PCI FFR is limited. Murray law-based quantitative flow ratio (μQFR) may represent a promising alternative, as it can quickly compute FFR from a single angiographic view.<h4>Objectives</h4>The authors aimed to investigate the potential role of post-PCI μQFR in predicting clinical outcomes.<h4>Methods</h4>This was a post hoc blinded analysis of the FLAVOUR trial. Patients with angiographically intermediate lesions randomized 1:1 to receive FFR or intravascular ultrasound-guided PCI were included. Post-PCI μQFR was assessed in successfully stented vessels, blinded to clinical outcoJACC. Asia59-70https://www.ebi.ac.uk/biostudies/studies/S-EPMC11775804biostudies-literaturePrognostic Value of Postpercutaneous Coronary Intervention Murray-Law-Based Quantitative Flow Ratio: Post Hoc Analysis From FLAVOUR Trial.PMC11775804Wijns WHahn JYZhang JHuang JJiang FYoon MHDing DWu PHu XWang JLee BKTang LKoo BKJiang WYu WAhn SGChen XTahk SJKang JWang ZZhou HKi YJChen PShin ESPu JTu SDoh JHKim WHe WKim UNam CWShi HfalsePrognostic Value of Postpercutaneous Coronary Intervention Murray-Law-Based Quantitative Flow Ratio: Post Hoc Analysis From FLAVOUR Trial.<h4>Background</h4>Coronary physiology measured by fractional flow reserve (FFR) is superior to angiography for assessing the efficacy of percutaneous coronary intervention (PCI). Yet, the clinical adoption of post-PCI FFR is limited. Murray law-based quantitative flow ratio (μQFR) may represent a promising alternative, as it can quickly compute FFR from a single angiographic view.<h4>Objectives</h4>The authors aimed to investigate the potential role of post-PCI μQFR in predicting clinical outcomes.<h4>Methods</h4>This was a post hoc blinded analysis of the FLAVOUR trial. Patients with angiographically intermediate lesions randomized 1:1 to receive FFR or intravascular ultrasound-guided PCI were included. Post-PCI μQFR was assessed in successfully stented vessels, blinded to clinical outco2025-01-01T00:00:00Z2025 Jan2026-06-02T10:11:31.248Z2025-04-05T23:35:08.625ZS-EPMC117758043988619310.1016/j.jacasi.2024.10.019