biostudies-literatureUnknown5(1)Lukey A<h4>Abstract</h4>With evidence that salpingectomy is effective in preventing high-grade serous carcinoma, it is time to consider offering this procedure to people at higher-than-average lifetime risk for ovarian cancer, despite not having a pathogenic genetic variant that increases the risk for ovarian cancer. This targeted approach has potential to be effective at reducing ovarian cancer incidence, and unlike opportunistic salpingectomy, it is focused on people with an increased lifetime risk of ovarian cancer. However, the acceptability of this approach within the population of potential patients remains unknown. We conducted an online survey of adults in British Columbia, Canada, who were defined as “at risk” for ovarian cancer (i.e., people born with ovaries). Participants completed a Cancer research communications187-194https://www.ebi.ac.uk/biostudies/studies/S-EPMC11780486biostudies-literatureEvaluating Ovarian Cancer Risk-Reducing Salpingectomy Acceptance: A Survey.PMC11780486Sowamber RLukey AHuntsman DHoward AFHanley GEPhung MTMeza RPearce CLLaw MRfalseEvaluating Ovarian Cancer Risk-Reducing Salpingectomy Acceptance: A Survey.<h4>Abstract</h4>With evidence that salpingectomy is effective in preventing high-grade serous carcinoma, it is time to consider offering this procedure to people at higher-than-average lifetime risk for ovarian cancer, despite not having a pathogenic genetic variant that increases the risk for ovarian cancer. This targeted approach has potential to be effective at reducing ovarian cancer incidence, and unlike opportunistic salpingectomy, it is focused on people with an increased lifetime risk of ovarian cancer. However, the acceptability of this approach within the population of potential patients remains unknown. We conducted an online survey of adults in British Columbia, Canada, who were defined as “at risk” for ovarian cancer (i.e., people born with ovaries). Participants completed a 2025-01-01T00:00:00Z2025 Jan2026-06-01T20:07:27.405Z2025-04-04T14:04:42.743ZS-EPMC117804863978567810.1158/2767-9764.CRC-24-0566