biostudies-literatureUnknown22(3)Cao S<b><i>Background:</i></b> Recent research emphasizes the significant regulatory functions of epigenetic alterations and post-translational modifications (PTMs) in the ferroptosis process. Despite the existing volume of literature, there is a remarkable shortage of comprehensive analyses that systematically trace the evolution of research, map key investigative routes, evaluate the current situation of the field, determine central themes, and predict future directions. This study intends to offer a comprehensive summary of the progress achieved during the past 12 years in comprehending how epigenetic modifications and PTMs regulate ferroptosis. <b><i>Methods:</i></b> The dataset originated from the Web of Science, covering the period from January 1, 2012, to May 21, 2024. By employing advanInternational journal of medical sciences508-527https://www.ebi.ac.uk/biostudies/studies/S-EPMC11783085biostudies-literatureDeciphering Epigenetic and Post-Translational Modifications in Ferroptosis: A Scientometric and Visualization Study.PMC11783085Wang DXiong ACao SZeng HWei YYue YfalseDeciphering Epigenetic and Post-Translational Modifications in Ferroptosis: A Scientometric and Visualization Study.<b><i>Background:</i></b> Recent research emphasizes the significant regulatory functions of epigenetic alterations and post-translational modifications (PTMs) in the ferroptosis process. Despite the existing volume of literature, there is a remarkable shortage of comprehensive analyses that systematically trace the evolution of research, map key investigative routes, evaluate the current situation of the field, determine central themes, and predict future directions. This study intends to offer a comprehensive summary of the progress achieved during the past 12 years in comprehending how epigenetic modifications and PTMs regulate ferroptosis. <b><i>Methods:</i></b> The dataset originated from the Web of Science, covering the period from January 1, 2012, to May 21, 2024. By employing advan2025-01-01T00:00:00Z20252025-04-22T10:28:08.891Z2025-04-05T23:34:54.104ZS-EPMC117830853989825810.7150/ijms.104222