biostudies-literatureZavatta GMinistero della Salute139-150https://www.ebi.ac.uk/biostudies/studies/S-EPMC11794375biostudies-literatureUnknown20(1)Liver transplantation (LT) has historically been associated with a high prevalence of osteoporosis, but most of the available data date back to late 1990s-early 2000s with limited sample size. Our aim was to assess the prevalence of bone fragility fractures and contributing factors in a large modern cohort of liver transplant recipients. Retrospective study of 429 consecutive patients receiving liver transplantation from 1/1/2010 to 31/12/2015. Final cohort included 366 patients. Electronic radiological images (lateral views of spine X-rays or Scout CT abdominal scans) performed within 6 months from LT, were blinded reviewed to screen for morphometric vertebral fractures. Symptomatic clinical fragility fractures were recorded from the medical records. Patients with fragility fractures in tInternal and emergency medicineHigh bone fracture risk in a large modern cohort of liver transplant recipients.PMC11794375RC-2024-2789954Roberto Di DonatoFrancesca CaputoCappa FMVittoria VeroZavatta GSonia BerardiLetizia Anna MarcantoniMorelli MCTurco LAnna BaldanVitale GAltieri PPagotto UPianta PCescon MPiscaglia FMariachiara CorradoBOLTBO study group Luca VizioliRavaioli MfalseHigh bone fracture risk in a large modern cohort of liver transplant recipients.Liver transplantation (LT) has historically been associated with a high prevalence of osteoporosis, but most of the available data date back to late 1990s-early 2000s with limited sample size. Our aim was to assess the prevalence of bone fragility fractures and contributing factors in a large modern cohort of liver transplant recipients. Retrospective study of 429 consecutive patients receiving liver transplantation from 1/1/2010 to 31/12/2015. Final cohort included 366 patients. Electronic radiological images (lateral views of spine X-rays or Scout CT abdominal scans) performed within 6 months from LT, were blinded reviewed to screen for morphometric vertebral fractures. Symptomatic clinical fragility fractures were recorded from the medical records. Patients with fragility fractures in t2025-01-01T00:00:00Z2025 Jan2025-04-04T07:26:59.93Z2025-04-04T07:26:59.93ZS-EPMC117943753933131310.1007/s11739-024-03767-5