{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Fan L"],"funding":["Zhejiang Province Traditional Chinese Medicine Science and Technology Project","National Natural Science Foundation of China"],"pagination":["38"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11796166"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["24(1)"],"pubmed_abstract":["<h4>Background</h4>This study aimed to analyse the relationship of the blood lipid profile and interleukin-6 (IL-6) with osteoporosis and osteopenia and to explore the predictive value of the combined application of these biomarkers in osteoporosis and osteopenia.<h4>Methods</h4>Data from 276 patients treated in the orthopaedics department were retrospectively analysed. Their general information was collected, and the relationships among the blood lipid profile, IL-6 with bone turnover markers, and bone mineral density (BMD) were analysed. Patients were categorized based on their T scores for intergroup comparisons. Finally, the diagnostic efficiency of lipid metabolism markers and IL-6 for osteoporosis and osteopenia was assessed using receiver operating characteristic (ROC) curves.<h4>Re"],"journal":["Lipids in health and disease"],"pubmed_title":["The diagnostic value of the combined application of blood lipid metabolism markers and interleukin-6 in osteoporosis and osteopenia."],"pmcid":["PMC11796166"],"funding_grant_id":["2023ZL461","81873128"],"pubmed_authors":["Yang Y","Chen J","Chen Z","Zhang Y","Fan L","Chen C"],"additional_accession":[]},"is_claimable":false,"name":"The diagnostic value of the combined application of blood lipid metabolism markers and interleukin-6 in osteoporosis and osteopenia.","description":"<h4>Background</h4>This study aimed to analyse the relationship of the blood lipid profile and interleukin-6 (IL-6) with osteoporosis and osteopenia and to explore the predictive value of the combined application of these biomarkers in osteoporosis and osteopenia.<h4>Methods</h4>Data from 276 patients treated in the orthopaedics department were retrospectively analysed. Their general information was collected, and the relationships among the blood lipid profile, IL-6 with bone turnover markers, and bone mineral density (BMD) were analysed. Patients were categorized based on their T scores for intergroup comparisons. Finally, the diagnostic efficiency of lipid metabolism markers and IL-6 for osteoporosis and osteopenia was assessed using receiver operating characteristic (ROC) curves.<h4>Re","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Feb","modification":"2025-04-18T13:02:05.208Z","creation":"2025-04-06T22:26:11.716Z"},"accession":"S-EPMC11796166","cross_references":{"pubmed":["39910539"],"doi":["10.1186/s12944-025-02456-2"]}}