{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Sundermeyer J"],"funding":["British Heart Foundation"],"pagination":["40-50"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11798633"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["27(1)"],"pubmed_abstract":["<h4>Aims</h4>The optimal timing for implementing mechanical circulatory support (MCS) in cardiogenic shock (CS) remains indeterminate. This study aims to evaluate patient characteristics and outcome associated with the time interval between CS onset and veno-arterial extracorporeal membrane oxygenation (VA-ECMO) implementation.<h4>Methods and results</h4>In this study, patients with CS treated with MCS at 15 tertiary care centres in three countries were enrolled. Patients treated with MCS were stratified into early (<2 h), intermediate (2-12 h) and delayed (≥12-24 h) MCS implantation by using the time interval between CS onset and MCS device implementation. Adjusted logistic and Cox regression models were fitted to assess the association between timing of MCS implementation, patient charac"],"journal":["European journal of heart failure"],"pubmed_title":["Timing of veno-arterial extracorporeal membrane oxygenation support in patients with cardiogenic shock."],"pmcid":["PMC11798633"],"funding_grant_id":["PG/20/22/35093","PG/17/30/32961","AA/18/2/34218"],"pubmed_authors":["Beer BN","von Lewinski D","Blankenberg S","Frey N","Thiele H","Kellner C","Mangner N","Krais J","Sundermeyer J","Eitel I","Scherer C","Frank D","Nordbeck P","Westermann D","Besch L","Mobius-Winkler S","Graf T","Skurk C","Sag CM","Dettling A","Schrage B","Kirchhof P","Pauschinger M","Orban M"],"additional_accession":[]},"is_claimable":false,"name":"Timing of veno-arterial extracorporeal membrane oxygenation support in patients with cardiogenic shock.","description":"<h4>Aims</h4>The optimal timing for implementing mechanical circulatory support (MCS) in cardiogenic shock (CS) remains indeterminate. This study aims to evaluate patient characteristics and outcome associated with the time interval between CS onset and veno-arterial extracorporeal membrane oxygenation (VA-ECMO) implementation.<h4>Methods and results</h4>In this study, patients with CS treated with MCS at 15 tertiary care centres in three countries were enrolled. Patients treated with MCS were stratified into early (<2 h), intermediate (2-12 h) and delayed (≥12-24 h) MCS implantation by using the time interval between CS onset and MCS device implementation. Adjusted logistic and Cox regression models were fitted to assess the association between timing of MCS implementation, patient charac","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Jan","modification":"2026-06-02T10:17:12.226Z","creation":"2025-04-04T07:26:45.377Z"},"accession":"S-EPMC11798633","cross_references":{"pubmed":["39444297"],"doi":["10.1002/ejhf.3498"]}}