{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Takamatsu T"],"funding":["MEXT | Japan Society for the Promotion of Science (JSPS)"],"pagination":["120-128"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11799345"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["134(2)"],"pubmed_abstract":["Male-killing is a microbe-induced reproductive manipulation in invertebrates whereby male hosts are eliminated during development. In the tea tortrix moth Homona magnanima, Osugoroshi viruses 1‒3 (OGVs), belonging to Partitiviridae induce male-killing. The infection patterns of OGVs are diverse; however, how the influence of these patterns of host phenotypes remains largely unknown. Using field-collected larvae, we established a OGV1 and OGV3 double-infection line, in addition to a triple-infection line, and examined the dsRNA segments, purified viral proteins, OGV density, and host phenotypes. PCR analysis demonstrated that the triple-infection line lost one dsRNA segment, whereas the double-infection line lost eight segments, including one RNA-dependent RNA polymerase (RdRp) gene. LC-MS "],"journal":["Heredity"],"pubmed_title":["Infection pattern of male-killing viruses alters phenotypes in the tea tortrix moth Homona magnanima."],"pmcid":["PMC11799345"],"funding_grant_id":["22KJ1247"],"pubmed_authors":["Kitaura K","Takamatsu T","Kozono T","Itoh Y","Moriyama H","Wu CF","Inoue MN","Arai H"],"additional_accession":[]},"is_claimable":false,"name":"Infection pattern of male-killing viruses alters phenotypes in the tea tortrix moth Homona magnanima.","description":"Male-killing is a microbe-induced reproductive manipulation in invertebrates whereby male hosts are eliminated during development. In the tea tortrix moth Homona magnanima, Osugoroshi viruses 1‒3 (OGVs), belonging to Partitiviridae induce male-killing. The infection patterns of OGVs are diverse; however, how the influence of these patterns of host phenotypes remains largely unknown. Using field-collected larvae, we established a OGV1 and OGV3 double-infection line, in addition to a triple-infection line, and examined the dsRNA segments, purified viral proteins, OGV density, and host phenotypes. PCR analysis demonstrated that the triple-infection line lost one dsRNA segment, whereas the double-infection line lost eight segments, including one RNA-dependent RNA polymerase (RdRp) gene. LC-MS ","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Feb","modification":"2026-06-16T07:11:31.651Z","creation":"2026-06-16T03:10:09.392Z"},"accession":"S-EPMC11799345","cross_references":{"pubmed":["39725691"],"doi":["10.1038/s41437-024-00741-x"]}}