{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["29(1)"],"submitter":["Marco DN"],"pubmed_abstract":["<h4>Background</h4>Time to positivity (TTP) and differential TTP (DTP) emerge as diagnostic and prognostic tools for bloodstream infections (BSI) though specific cut-off values need to be determined for each pathogen. Pseudomonas aeruginosa BSI (PAE-BSI) is of critical concern, particularly in immunocompromised patients, due to high mortality rates. Catheter-related infections are a common cause, necessitating rapid and accurate diagnostic tools for effective management (source-control).<h4>Methods</h4>Unicentric retrospective observational study analyzing the diagnostic utility and best cut-off values of time to positivity (TTP) and differential time to positivity (DTP) to identify catheter-related PAE-BSI and the association of TTP with 30-day mortality.<h4>Results</h4>1177 PAE-BSI cases"],"journal":["Critical care (London, England)"],"pagination":["63"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11800533"],"repository":["biostudies-literature"],"pubmed_title":["Time to positivity as a predictor of catheter-related bacteremia and mortality in adults with Pseudomonas aeruginosa bloodstream infection."],"pmcid":["PMC11800533"],"pubmed_authors":["Anguera S","Monzo-Gallo P","Brey M","Verdejo MA","Martinez JA","Del Rio A","Chumbita M","Puerta-Alcalde P","Casals-Pascual C","Hernandez-Meneses M","Cuervo G","Soriano A","Pitart C","Aiello TF","Herrera S","Marco DN","Morata L","Cardozo C","Espasa M","Mensa J","Sempere A","Garcia F","Bodro M","Garcia-Vidal C","Grafia I"],"additional_accession":[]},"is_claimable":false,"name":"Time to positivity as a predictor of catheter-related bacteremia and mortality in adults with Pseudomonas aeruginosa bloodstream infection.","description":"<h4>Background</h4>Time to positivity (TTP) and differential TTP (DTP) emerge as diagnostic and prognostic tools for bloodstream infections (BSI) though specific cut-off values need to be determined for each pathogen. Pseudomonas aeruginosa BSI (PAE-BSI) is of critical concern, particularly in immunocompromised patients, due to high mortality rates. Catheter-related infections are a common cause, necessitating rapid and accurate diagnostic tools for effective management (source-control).<h4>Methods</h4>Unicentric retrospective observational study analyzing the diagnostic utility and best cut-off values of time to positivity (TTP) and differential time to positivity (DTP) to identify catheter-related PAE-BSI and the association of TTP with 30-day mortality.<h4>Results</h4>1177 PAE-BSI cases","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Feb","modification":"2025-04-21T15:56:02.88Z","creation":"2025-04-21T15:56:02.88Z"},"accession":"S-EPMC11800533","cross_references":{"pubmed":["39910660"],"doi":["10.1186/s13054-025-05292-z"]}}