biostudies-literatureGiampaolo FMinistero dell'Universit? e della Ricerca2503-2510https://www.ebi.ac.uk/biostudies/studies/S-EPMC11801656biostudies-literatureUnknown97(4)Polyolefins are unique among synthetic polymers because their wide application envelope originates from a finely controlled microstructure of hydrocarbon chains, lacking any distinctive functional groups. This hampers the methods of automated sorting based on vibrational spectroscopies and calls for much more complex ¹³C NMR elucidations. High-temperature cryoprobes have dramatically shortened the acquisition time of ¹³C NMR spectra, and few minutes are now enough for polyolefin classification purposes; however, conventional data analysis remains labor and time-consuming. In this paper, we introduce an instrument for automated fast determinations of the ¹³C NMR microstructure on polyolefin materials, implemented by integrating High-Throughput ExperimentatioAnalytical chemistryAutomated Ultra-Fast <sup>13</sup>C NMR Analysis of Polyolefin Materials.PMC11801656CUP E53D23016000001CUP E63C22000980007Busico VGiampaolo FCuomo SPiccialli FCipullo RfalseAutomated Ultra-Fast <sup>13</sup>C NMR Analysis of Polyolefin Materials.Polyolefins are unique among synthetic polymers because their wide application envelope originates from a finely controlled microstructure of hydrocarbon chains, lacking any distinctive functional groups. This hampers the methods of automated sorting based on vibrational spectroscopies and calls for much more complex ¹³C NMR elucidations. High-temperature cryoprobes have dramatically shortened the acquisition time of ¹³C NMR spectra, and few minutes are now enough for polyolefin classification purposes; however, conventional data analysis remains labor and time-consuming. In this paper, we introduce an instrument for automated fast determinations of the ¹³C NMR microstructure on polyolefin materials, implemented by integrating High-Throughput Experimentatio2025-01-01T00:00:00Z2025 Feb2025-04-26T01:46:04.165Z2025-04-26T01:46:04.165ZS-EPMC118016563983553310.1021/acs.analchem.4c06290