{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10(3)"],"submitter":["Schneider TR"],"pubmed_abstract":["<h4>Introduction</h4>Sex differences in stroke incidence, vascular risk factors (VRFs), and etiologies among young adults remain underexplored, particularly regarding age-related patterns.<h4>Patients and methods</h4>We retrospectively analyzed young adults (18-55 years) with first-ever ischemic stroke treated at certified acute stroke units/centers between 2014 and 2022, using Swiss Stroke Registry data. Stroke rates (per 100,000 person-years), VRFs, and etiologies were assessed by age and sex.<h4>Results</h4>Among 3,995 stroke patients, stroke rates were similar between sexes until age 35, after which men showed a more pronounced exponential increase. This rise was particularly notable in patients with elevated BMI and ⩾2 VRFs. The proportion of patients with ⩾2 VRFs rose with age (18-35"],"journal":["European stroke journal"],"pagination":["882-891"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11803591"],"repository":["biostudies-literature"],"pubmed_title":["First ischemic stroke in young adults: Sex and age-related differences in stroke rates, risk factors, and etiologies."],"pmcid":["PMC11803591"],"pubmed_authors":["Arnold M","Bolognese M","Humm AM","Heldner M","Albert S","Dirren E","Dittrich TD","Katan M","Kahles T","Nedeltchev K","Medlin F","Tarnutzer AA","Peters N","Baumgartner M","Luft AR","Bonati LH","Mordasini P","Berger C","Cereda CW","Renaud S","Schneider TR","Mono ML","Siebel P","Rodic B","Michel P","De Marchis GM","Sturzenegger R","Vehoff J"],"additional_accession":[]},"is_claimable":false,"name":"First ischemic stroke in young adults: Sex and age-related differences in stroke rates, risk factors, and etiologies.","description":"<h4>Introduction</h4>Sex differences in stroke incidence, vascular risk factors (VRFs), and etiologies among young adults remain underexplored, particularly regarding age-related patterns.<h4>Patients and methods</h4>We retrospectively analyzed young adults (18-55 years) with first-ever ischemic stroke treated at certified acute stroke units/centers between 2014 and 2022, using Swiss Stroke Registry data. Stroke rates (per 100,000 person-years), VRFs, and etiologies were assessed by age and sex.<h4>Results</h4>Among 3,995 stroke patients, stroke rates were similar between sexes until age 35, after which men showed a more pronounced exponential increase. This rise was particularly notable in patients with elevated BMI and ⩾2 VRFs. The proportion of patients with ⩾2 VRFs rose with age (18-35","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-06-02T00:14:31.757Z","creation":"2025-04-05T09:40:40.252Z"},"accession":"S-EPMC11803591","cross_references":{"pubmed":["39916317"],"doi":["10.1177/23969873251317347"]}}