biostudies-literatureUnknown24Saeed H<h4>Background</h4>Cancer patients are at an increased risk for the incidence and complications of acute myocardial infarction (AMI) due to shared risk factors and treatment-related adverse effects. Mortality trends for AMI-related deaths in adult cancer patients in the U.S. remain unexplored.<h4>Methodology</h4>This study used CDC WONDER data for death certificates from 1999 to 2020, identifying U.S. adults (≥25 years) with cancer (ICD-10: C00-D49) who died of AMI (ICD-10: I21) as the underlying cause. Age-adjusted mortality rates (AAMRs) and annual percent changes (APCs) were calculated and stratified by gender, age, race, and geographic location.<h4>Results</h4>Between 1999 and 2020, there were 109,462 AMI-related deaths in adult cancer patients. The AAMR decreased from 4.3 per 100,000 International journal of cardiology. Cardiovascular risk and prevention200371https://www.ebi.ac.uk/biostudies/studies/S-EPMC11803891biostudies-literatureUnraveling trends and disparities in acute myocardial infarction-related mortality among adult cancer patients: A nationwide CDC-WONDER analysis (1999-2020).PMC11803891Shahid SMajeed USaeed HHussain ATSiddiqui MRIftikhar HACh IATahirkheli NKIqbal MKhalid SfalseUnraveling trends and disparities in acute myocardial infarction-related mortality among adult cancer patients: A nationwide CDC-WONDER analysis (1999-2020).<h4>Background</h4>Cancer patients are at an increased risk for the incidence and complications of acute myocardial infarction (AMI) due to shared risk factors and treatment-related adverse effects. Mortality trends for AMI-related deaths in adult cancer patients in the U.S. remain unexplored.<h4>Methodology</h4>This study used CDC WONDER data for death certificates from 1999 to 2020, identifying U.S. adults (≥25 years) with cancer (ICD-10: C00-D49) who died of AMI (ICD-10: I21) as the underlying cause. Age-adjusted mortality rates (AAMRs) and annual percent changes (APCs) were calculated and stratified by gender, age, race, and geographic location.<h4>Results</h4>Between 1999 and 2020, there were 109,462 AMI-related deaths in adult cancer patients. The AAMR decreased from 4.3 per 100,000 2025-01-01T00:00:00Z2025 Mar2025-04-04T01:33:30.108Z2025-04-04T01:33:30.108ZS-EPMC118038913992534510.1016/j.ijcrp.2025.200371