{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Yan X"],"funding":["Capital's Funds for Health Improvement and Research"],"pagination":["62"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11806895"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["25(1)"],"pubmed_abstract":["<h4>Objectives</h4>Postoperative nausea and vomiting (PONV) is common after video-assisted thoracic surgery, which may be associated with the use of intraoperative opioids. We tested the hypothesis that balanced opioid-free anesthesia (OFA) might reduce the incidence of PONV after video-assisted thoracic surgery.<h4>Methods</h4>One hundred and sixty-eight adults undergoing video-assisted thoracic assisted surgery were randomly assigned to receive balanced opioid-free anesthesia or balanced opioid-based anesthesia (OBA). The primary outcome was the incidence of PONV, which was assessed with the Myles's simplified PONV impact scale during the initial 24 h after surgery.<h4>Results</h4>Compared with OBA group, the overall incidence of PONV in OFA group was significant reduced (14.6% vs. 30.1%"],"journal":["BMC anesthesiology"],"pubmed_title":["Effects of balanced opioid-free anesthesia on post-operative nausea and vomiting in patients undergoing video-assisted thoracic surgery: a randomized trial."],"pmcid":["PMC11806895"],"funding_grant_id":["2022-2Z-2039"],"pubmed_authors":["Liang C","Jiang J","Ji Y","Wu AS","Wei CW","Yan X"],"additional_accession":[]},"is_claimable":false,"name":"Effects of balanced opioid-free anesthesia on post-operative nausea and vomiting in patients undergoing video-assisted thoracic surgery: a randomized trial.","description":"<h4>Objectives</h4>Postoperative nausea and vomiting (PONV) is common after video-assisted thoracic surgery, which may be associated with the use of intraoperative opioids. We tested the hypothesis that balanced opioid-free anesthesia (OFA) might reduce the incidence of PONV after video-assisted thoracic surgery.<h4>Methods</h4>One hundred and sixty-eight adults undergoing video-assisted thoracic assisted surgery were randomly assigned to receive balanced opioid-free anesthesia or balanced opioid-based anesthesia (OBA). The primary outcome was the incidence of PONV, which was assessed with the Myles's simplified PONV impact scale during the initial 24 h after surgery.<h4>Results</h4>Compared with OBA group, the overall incidence of PONV in OFA group was significant reduced (14.6% vs. 30.1%","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Feb","modification":"2026-06-02T07:13:13.861Z","creation":"2025-04-06T07:42:01.571Z"},"accession":"S-EPMC11806895","cross_references":{"pubmed":["39923016"],"doi":["10.1186/s12871-025-02938-x"]}}