{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["15(6)"],"submitter":["Manoj Kumar S"],"pubmed_abstract":["A new phenanthridine appended quinoline-based chemoreceptor 5-(5-(quinolin-8-yl)thiophen-2-yl)-tetrahydrodibenzo[a,i]phenanthridine (PHQBA) was successfully synthesized and characterized by <sup>1</sup>H, <sup>13</sup>C, and HRMS spectral analyses. The promising chelation-induced process in PHQBA was accelerated by Th<sup>4+</sup> ions, which impart robust ratiometric green fluorescence at 515 nm. The host-guest complex formed in a 1 : 1 binding stoichiometry between Th<sup>4+</sup> ions and PHQBA was demonstrated by Jobs plot experiments. The Benesi-Hildebrand (BH) plot was employed to compute the binding constant for the complexation of PHQBA + Th<sup>4+</sup>, which was determined to be 3.77 × 10<sup>5</sup> M<sup>-1</sup>. To comprehend the detection mechanism of PHQBA, DFT, and TDDFT,"],"journal":["RSC advances"],"pagination":["4546-4552"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11808482"],"repository":["biostudies-literature"],"pubmed_title":["Ratiometric discrimination of Th&lt;sup&gt;4+&lt;/sup&gt; ions by a fluorogenic quinoline appended phenanthridine sensor and its applications."],"pmcid":["PMC11808482"],"pubmed_authors":["Munusamy S","Manoj Kumar S","Enbanathan S","Kulathu Iyer S","Ranganadin S"],"additional_accession":[]},"is_claimable":false,"name":"Ratiometric discrimination of Th&lt;sup&gt;4+&lt;/sup&gt; ions by a fluorogenic quinoline appended phenanthridine sensor and its applications.","description":"A new phenanthridine appended quinoline-based chemoreceptor 5-(5-(quinolin-8-yl)thiophen-2-yl)-tetrahydrodibenzo[a,i]phenanthridine (PHQBA) was successfully synthesized and characterized by <sup>1</sup>H, <sup>13</sup>C, and HRMS spectral analyses. The promising chelation-induced process in PHQBA was accelerated by Th<sup>4+</sup> ions, which impart robust ratiometric green fluorescence at 515 nm. The host-guest complex formed in a 1 : 1 binding stoichiometry between Th<sup>4+</sup> ions and PHQBA was demonstrated by Jobs plot experiments. The Benesi-Hildebrand (BH) plot was employed to compute the binding constant for the complexation of PHQBA + Th<sup>4+</sup>, which was determined to be 3.77 × 10<sup>5</sup> M<sup>-1</sup>. To comprehend the detection mechanism of PHQBA, DFT, and TDDFT,","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Feb","modification":"2025-04-26T16:28:41.649Z","creation":"2025-04-06T15:14:46.948Z"},"accession":"S-EPMC11808482","cross_references":{"pubmed":["39931419"],"doi":["10.1039/d4ra08840a"]}}