biostudies-literatureMai YSuzhou Foreign Academician WorkstationNational Natural Science Foundation of ChinaEngineering and Physical Sciences Research Councile2410680https://www.ebi.ac.uk/biostudies/studies/S-EPMC11809376biostudies-literatureUnknown12(6)Hydrogen peroxide (H₂O₂) is an important chemical in synthetic chemistry with huge demands. Photocatalytic synthesis of H₂O₂ via oxygen reduction and water oxidation reactions (ORR and WOR) is considered as a promising and desirable solution for on-site applications. However, the efficiency of such a process is low due to the poor solubility of molecular oxygen and the rapid reverse reaction of hydroxyl radicals (^•OH) with hydrogen atoms (H). Here, a strategy is proposed to boost the H₂O₂ evolution via oxidation of water by employing a H acceptor (A, nitrocyclohexane), an ^•OH mediator (M, dioxane), and a photocatalyst (CdS nanosheets). While ^•OH radicals are stabilized by dioxane to produce kAdvanced science (Weinheim, Baden-Wurttemberg, Germany)Photocatalytic Partial Water Oxidation Promoted by a Hydrogen Acceptor-Hydroxyl Mediator Couple.PMC11809376EP/T013079/1SWY202200122472112Zhang DLi JMai YCai NZhang KLiang WLim TWang CMaliutina KNiemantsverdriet HRichards EZhang WLi YSu RHuang YBesenbacher FLeng XShen YfalsePhotocatalytic Partial Water Oxidation Promoted by a Hydrogen Acceptor-Hydroxyl Mediator Couple.Hydrogen peroxide (H₂O₂) is an important chemical in synthetic chemistry with huge demands. Photocatalytic synthesis of H₂O₂ via oxygen reduction and water oxidation reactions (ORR and WOR) is considered as a promising and desirable solution for on-site applications. However, the efficiency of such a process is low due to the poor solubility of molecular oxygen and the rapid reverse reaction of hydroxyl radicals (^•OH) with hydrogen atoms (H). Here, a strategy is proposed to boost the H₂O₂ evolution via oxidation of water by employing a H acceptor (A, nitrocyclohexane), an ^•OH mediator (M, dioxane), and a photocatalyst (CdS nanosheets). While ^•OH radicals are stabilized by dioxane to produce k2025-01-01T00:00:00Z2025 Feb2025-04-04T23:56:48.21Z2025-04-04T23:56:48.21ZS-EPMC118093763970770210.1002/advs.202410680