biostudies-literatureDohata MJST-Mirai ProgramMoonshot Research and Development ProgramNakatomi FoundationTateishi Science and Technology FoundationNakatani FoundationPrecursory Research for Embryonic Science and TechnologyJapan Society for the Promotion of Science (JSPS) WAKATEe70021https://www.ebi.ac.uk/biostudies/studies/S-EPMC11831245biostudies-literatureUnknown61(4)Interoception, the internal perception of bodily states such as heartbeat and hunger, plays a crucial role in shaping cognitive and emotional states. Since postural control affects cognitive and emotional processing, exploring postural effects on interoception could help uncover the neural mechanisms underlying its effects on cognition and emotion. In this study, we aimed to investigate how different postures affect interoception by using heartbeat-evoked potentials (HEPs), which reflect the cortical processing of cardiac signals. Two experiments were conducted; Experiment 1 involved 47 healthy male participants comparing sitting and standing postures, and Experiment 2 involved 24 healthy male participants comparing stable and unstable standing conditions. HEPs were analyzed using cluster-The European journal of neurosciencePosture-Dependent Modulation of Interoceptive Processing in Young Male Participants: A Heartbeat-Evoked Potential Study.PMC11831245Research Grant (A)#JP20349063#JPMJMS2012#JPMJPR24I550969285Nakazawa KKaneko NTakahashi RDohata MSuzuki YfalsePosture-Dependent Modulation of Interoceptive Processing in Young Male Participants: A Heartbeat-Evoked Potential Study.Interoception, the internal perception of bodily states such as heartbeat and hunger, plays a crucial role in shaping cognitive and emotional states. Since postural control affects cognitive and emotional processing, exploring postural effects on interoception could help uncover the neural mechanisms underlying its effects on cognition and emotion. In this study, we aimed to investigate how different postures affect interoception by using heartbeat-evoked potentials (HEPs), which reflect the cortical processing of cardiac signals. Two experiments were conducted; Experiment 1 involved 47 healthy male participants comparing sitting and standing postures, and Experiment 2 involved 24 healthy male participants comparing stable and unstable standing conditions. HEPs were analyzed using cluster-2025-01-01T00:00:00Z2025 Feb2025-04-04T02:04:52.082Z2025-04-04T02:04:52.082ZS-EPMC118312453995744210.1111/ejn.70021