{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Clarke KM"],"funding":["NIA NIH HHS","Baptist Foundation of San Antonio Endowment","NINDS NIH HHS","NIH","Owens Foundation"],"pagination":["e14626"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11852352"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["21(2)"],"pubmed_abstract":["The Nun Study is an iconic longitudinal study of aging and dementia on a cohort of 678 Catholic nuns from the School Sisters of Notre Dame. Participants consented to undergoing annual neuropsychological assessments, allowing researchers access to convent archives and medical records and post mortem brain donation. This study investigated the associations between epidemiological factors, cognitive function, and brain pathology. By examining published literature that reports on or utilizes Nun Study data, we provide an overview of its methodology and key findings, emphasizing its significant contributions to understanding cognitive impairment and related neuropathologies. Seminal findings on early-life factors affecting cognitive health, clinicopathological correlations, and apparent resista"],"journal":["Alzheimer's & dementia : the journal of the Alzheimer's Association"],"pubmed_title":["The Nun Study: Insights from 30 years of aging and dementia research."],"pmcid":["PMC11852352"],"funding_grant_id":["R01 AG082118","R01 AG072080","U24 NS133945","P30AG066546","U24NS133945","P30 AG066546","K08 AG065463","RF1 AG072080"],"pubmed_authors":["Babu S","Salardini A","Dopler M","Alhneif M","Gonzalez AD","Etemadmoghadam S","Ogunbona OB","Ghaseminejad-Bandpey A","Flanagan ME","Clarke KM","Danner B","Parker-Garza J","Corbett C"],"additional_accession":[]},"is_claimable":false,"name":"The Nun Study: Insights from 30 years of aging and dementia research.","description":"The Nun Study is an iconic longitudinal study of aging and dementia on a cohort of 678 Catholic nuns from the School Sisters of Notre Dame. Participants consented to undergoing annual neuropsychological assessments, allowing researchers access to convent archives and medical records and post mortem brain donation. This study investigated the associations between epidemiological factors, cognitive function, and brain pathology. By examining published literature that reports on or utilizes Nun Study data, we provide an overview of its methodology and key findings, emphasizing its significant contributions to understanding cognitive impairment and related neuropathologies. Seminal findings on early-life factors affecting cognitive health, clinicopathological correlations, and apparent resista","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Feb","modification":"2025-04-22T18:50:30.692Z","creation":"2025-04-06T02:36:56.884Z"},"accession":"S-EPMC11852352","cross_references":{"pubmed":["39998266"],"doi":["10.1002/alz.14626"]}}