biostudies-literatureFrolova NMinistry of Science and Higher Education of the Russian Federation290https://www.ebi.ac.uk/biostudies/studies/S-EPMC11852571biostudies-literatureUnknown15(2)Infection of higher plants with agrobacteria (<i>Agrobacterium tumefaciens</i>) represents one of the most comprehensively characterized examples of plant-microbial interactions. Incorporation of the bacterial transfer DNA (T-DNA) in the plant genome results in highly efficient expression of the bacterial auxin, cytokinin and opine biosynthesis genes, as well as the host genes of hormone-mediated signaling. These transcriptional events trigger enhanced proliferation of plant cells and formation of crown gall tumors. Because of this, infection of plant tissues with <i>A. tumefaciens</i> provides a convenient model to address the dynamics of cell metabolism accompanying plant development. To date, both early and late plant responses to agrobacterial infection are well-characterized at the leBiomoleculesProteome and Metabolome Alterations in Radish (<i>Raphanus sativus</i> L.) Seedlings Induced by Inoculation with <i>Agrobacterium tumefaciens</i>.PMC11852571075-15-2022-322Frolova NDodueva IBilova TOrlova AFedoseeva KLutova LAGorbach DFrolov AIhling CLukasheva EfalseProteome and Metabolome Alterations in Radish (<i>Raphanus sativus</i> L.) Seedlings Induced by Inoculation with <i>Agrobacterium tumefaciens</i>.Infection of higher plants with agrobacteria (<i>Agrobacterium tumefaciens</i>) represents one of the most comprehensively characterized examples of plant-microbial interactions. Incorporation of the bacterial transfer DNA (T-DNA) in the plant genome results in highly efficient expression of the bacterial auxin, cytokinin and opine biosynthesis genes, as well as the host genes of hormone-mediated signaling. These transcriptional events trigger enhanced proliferation of plant cells and formation of crown gall tumors. Because of this, infection of plant tissues with <i>A. tumefaciens</i> provides a convenient model to address the dynamics of cell metabolism accompanying plant development. To date, both early and late plant responses to agrobacterial infection are well-characterized at the le2025-01-01T00:00:00Z2025 Feb2025-04-04T01:12:29.613Z2025-04-04T01:12:29.613ZS-EPMC118525714000159310.3390/biom15020290