biostudies-literatureBajor JUniversity Research Grant ProgramUniversity of Pécs, Medical SchoolNational Research, Development, and Innovation OfficeMinistry of Culture and Innovation, National Fund for Research, Development and Innovation55https://www.ebi.ac.uk/biostudies/studies/S-EPMC11856780biostudies-literatureUnknown15(2)<b>Background:</b> The clinical presentation of coeliac disease (CD) is various and may influence disease course. We aimed to investigate the associations of clinical presentation with comorbidities and disease complications in a cohort of Hungarian coeliac patients. <b>Methods:</b> In this retrospective study, data of consecutive CD patients were analysed. Clinical presentation (classical vs. non-classical), extraintestinal manifestations and comorbidities (anaemia, metabolic bone disease, dermatitis herpetiformis, IgA deficiency, chromosomal abnormalities, autoimmune diseases and malignancy) were assessed. Student's <i>t</i>-test (for age at diagnosis) and the Chi-squared test or Fisher's exact test (for categorical variables) were applied as analyses. <b>Results:</b> A total of 738 patiJournal of personalized medicineAssociations of Clinical Presentation of Coeliac Disease with Comorbidities and Complications: A Retrospective Single-Centre Analysis.PMC11856780n/aEKÖP-24-4-IFK142942Bajor JPeresztegi MZSzigeti NVereczkei ZHegedus INagy EBencs RFarkas NSzakacs ZTarnok AfalseAssociations of Clinical Presentation of Coeliac Disease with Comorbidities and Complications: A Retrospective Single-Centre Analysis.<b>Background:</b> The clinical presentation of coeliac disease (CD) is various and may influence disease course. We aimed to investigate the associations of clinical presentation with comorbidities and disease complications in a cohort of Hungarian coeliac patients. <b>Methods:</b> In this retrospective study, data of consecutive CD patients were analysed. Clinical presentation (classical vs. non-classical), extraintestinal manifestations and comorbidities (anaemia, metabolic bone disease, dermatitis herpetiformis, IgA deficiency, chromosomal abnormalities, autoimmune diseases and malignancy) were assessed. Student's <i>t</i>-test (for age at diagnosis) and the Chi-squared test or Fisher's exact test (for categorical variables) were applied as analyses. <b>Results:</b> A total of 738 pati2025-01-01T00:00:00Z2025 Jan2025-04-04T02:45:43.734Z2025-04-04T02:45:43.734ZS-EPMC118567803999733210.3390/jpm15020055